3 products were found matching "Cay10318-%25"!
No results were found for the filter!
GW 5074
Item number: Cay10010368-25
Raf-1 is a proto-oncogene serine/threonine protein kinase that signals from Ras to the MAPK/ERK signaling pathway. This pathway mediates basic cellular functions, including proliferation, differentiation, and survival. GW 5074 is a potent, selective, and cell-permeable inhibitor of Raf-1 (IC50 = 9 nM). It blocks...
| Keywords: | 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one |
| Application: | Raf-1 inhbitor |
| CAS | 220904-83-6 |
| MW: | 520.9 D |
From 50.00€
*
PtdIns-(4,5)-P2-fluorescein (triethylammonium salt)
Item number: Cay10010388-25
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2-fluorescein is a fluorescent probe for any protein with a high-affinity binding interaction with...
| Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octadecanoylphosphatidyl)inositol-4,5-bisphosphate, pentatriethylammonium salt |
| Application: | Bioactive lipid assays |
| MW: | 1625.8 D |
From 115.00€
*
CB-13
Item number: Cay10010398-25
CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors. In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability. CB-13 does not possess genotoxic potential, as indicated by...
| Keywords: | CRA-13, 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone |
| Application: | Dual CB1 / CB2 receptor agonist |
| CAS | 432047-72-8 |
| MW: | 368.5 D |
From 74.00€
*
