3 products were found matching "Cay10317-%25"!

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Fluvastatin (sodium salt hydrate)
Fluvastatin (sodium salt hydrate)

Item number: Cay10010337-25

Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate
Application: Hydroxymethylglutaryl-coenzyme A reductase inhibitor
MW: 410.5 D
From 35.00€ *
Review
ZM 336372
ZM 336372

Item number: Cay10010367-25

The Ras/Raf-1 signalling pathway is a well-characterized system that links receptor tyrosine kinase (RTK) activation with changes in gene expression and cell behavior. Raf-1 is a serine/threonine protein kinase that phosphorylates and activates MAPK-kinase (MEK) in response to activation by Ras. ZM 336372 is a...
Keywords: 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]-benzamide
Application: Raf-1 inhibitor
CAS 208260-29-1
MW: 389.4 D
From 58.00€ *
Review
PAC-1
PAC-1

Item number: Cay10009317-25

Apoptosis can be induced when procaspase-3 is activated and converted to caspase-3. Procaspase-activating compound 1 (PAC-1) is a procaspase-3 activator and a potential drug treatment in cancer cell lines with elevated levels of procaspase-3. PAC-1's effectiveness was found to be directly proportional to the...
Keywords: Procaspase-activating Compound 1, 4-(phenylmethyl)-1-piperazineacetic acid,...
Application: Procaspase-3 activator
CAS 315183-21-2
MW: 392.5 D
From 145.00€ *
Review