- Search results for Cay10315
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6 products were found matching "Cay10315"!
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Item number: Cay10315-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Keywords: | SIRT6, SIR2L6, SIR2-like protein 6, SIR2-like protein 6, Regulatory protein SIR2 homolog 6, Regulatory protein SIR2... |
Application: | Enzyme kinetics, Inhibitor screening |
595.00€
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Item number: Cay10031-5
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at...
Keywords: | 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine |
Application: | Bioactive lipid assays |
CAS | 121324-31-0 |
MW: | 593.7 D |
From 126.00€
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Item number: Cay10311-5
(R)-(-)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(-)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and...
Keywords: | Ochracin, 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one |
Application: | Proliferation inhibitor |
CAS | 480-33-1 |
MW: | 178.2 D |
From 68.00€
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Item number: Cay11031-5
Farnesoid X receptor (FXR) is a nuclear receptor that is activated by bile acid, with chenodeoxycholic acid (CDCA) being a representative natural ligand. 6-ECDCA is a synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 = 99 nM). Through FXR, it alters gene expression that results in...
Keywords: | INT 747, Obeticholic Acid, (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid |
Application: | FXR agonist |
CAS | 459789-99-2 |
MW: | 420.6 D |
From 135.00€
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Item number: Cay10310-25
Cyclooxygenase metabolism of EPA to produce Prostaglandin E3 (PGE3) has been reported in biosynthetic preparations of ovine seminal vesicles and in the ocular tissues of primates. Prostaglandin A3 (PGA3) is an expected non-enzymatic dehydration product of this PGE3. PGA3 exhibits good affinity for the canine EP2 and...
Keywords: | PGA3, 9-oxo-15S-hydroxy-prosta-5Z,10,13E,17Z-tetraen-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 36614-31-0 |
MW: | 332.4 D |
From 130.00€
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Item number: Cay10312-25
F2 isoprostanes (F2-iPs) are thought to arise from the free radical-mediated peroxidation of phospholipid-bound arachidonic acid. They are cleaved, presumably by an unidentified phospholipase A2, and are found in the circulation and the urine. 8,12-iso-iPF2alpha-VI-1,5-lactone is a racemic mixture of the lactone...
Keywords: | 6-((E)-2-((1R,2S,3R,5S)-3,5-dihydroxy-2-((Z)-oct-2-enyl)cyclopentyl)vinyl)tetrahydro-2H-pyran-2-one |
Application: | Bioactive lipid assays |
MW: | 336.5 D |
From 156.00€
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