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19(R)-hydroxy Prostaglandin A2
19(R)-hydroxy Prostaglandin A2

Item number: Cay10295-50

Found in human seminal plasma, 19(R)-hydroxy prostaglandin A2 (19(R)-hydroxy PGA2) is presumed to be a non-enzymatic dehydration metabolite of 19(R)-hydroxy PGE2, which is also found in semen.Formal Name: 9-oxo-15S,19R-dihydroxy-prosta-5Z,10,13E-trien-1-oic acid. CAS Number: 52087-58-8. Synonyms: 19(R)-hydroxy PGA2....
Keywords: 19(R)-hydroxy PGA2, 9-oxo-15S,19R-dihydroxy-prosta-5Z,10,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 52087-58-8
MW: 350.5 D
From 88.00€ *
Review
MK-571
MK-571

Item number: Cay10029-5

MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...
Keywords: L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic...
Application: CysLT1 receptor antagonist
CAS 115104-28-4
MW: 515.1 D
From 43.00€ *
Review
SMI-4a
SMI-4a

Item number: Cay11029-5

The serine/threonine Pim kinases have been suggested to promote the activity of the rapamycin-sensitive mammalian target of rapamycin (mTORC1), which regulates cell growth and survival. Pim kinases are overexpressed in solid cancers and hematologic malignancies, and as such have become targets of small molecule...
Keywords: 5Z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
Application: Pim-1/Pim-2 kinase inhibitor
CAS 438190-29-5
MW: 273.2 D
From 60.00€ *
Review
17-phenyl trinor-13,14-dihydro Prostaglandin A2
17-phenyl trinor-13,14-dihydro Prostaglandin A2

Item number: Cay10290-5

17-phenyl trinor-13,14-dihydro Prostaglandin A2 is a synthetic PG analog whose biological activity has not been widely reported. The PGF2alpha analog latanoprost, which bears the same lower side chain features, has been approved as a pharmaceutical for the treatment of glaucoma.Formal Name:...
Keywords: 17-phenyl trinor-13,14-dihydro PGA2, 9-oxo-15R-hydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,10-dien-1-oic acid
Application: Bioactive lipid assays
CAS 130209-80-2
MW: 370.5 D
From 98.00€ *
Review