- Search results for Cay10272-%25
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5 products were found matching "Cay10272-%25"!
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Item number: Cay10722-25
JWH 302 (Cay-10722) is a cannabimimetic indole that shows 5-fold selectivity for the central cannabinoid (CB1) receptor with a Ki value of 17 nM compared to the peripheral cannabinoid (CB2) receptor (Ki = 89 nM). JWH 302 stimulates GTPgammaS binding of CB1 and CB2 receptors with EC50 values of 29.3 and 24.4 nM,...
Keywords: | 2-(3-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone |
Application: | Analytical reference standard, cannabimimetic indole |
CAS | 864445-45-4 |
MW: | 335.4 D |
From 276.00€
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Item number: Cay12027-25
OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM, Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid...
Keywords: | 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid |
Application: | DP2 antagonist |
CAS | 851723-84-7 |
MW: | 348.4 D |
From 92.00€
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Item number: Cay21027-25
Decylubiquinone is an analog of ubiquinone (coenzyme Q10, Cay-11506). It blocks reactive oxygen species production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition. Decylubiquinone inhibited opening of the mitochondrial permeability transition pore in response...
Keywords: | 2-decyl-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione |
Application: | ROS production blocker |
CAS | 55486-00-5 |
MW: | 322.4 D |
From 47.00€
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Item number: Cay13207-25
Phospholipase D (PLD) is an enzyme which cleaves the head group from phospholipids, producing the second messenger phosphatidic acid. Two mammalian isoforms of PLD, PLD1 and PLD2, have been identified, with multiple splice variants of each. Although the two isoforms share structural and functional features, they are...
Keywords: | N-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]dec-8-yl)ethyl]-2-naphthalenecarboxamide |
Application: | PLD2 inhibitor |
CAS | 1130067-34-3 |
MW: | 428.5 D |
From 68.00€
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Item number: Cay18207-25
The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC50 = 0.36 µM). It inhibits the related CCR1 receptor with an...
Keywords: | 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, monohydrochloride |
Application: | CCR2 antagonist |
CAS | 1173022-16-6 |
MW: | 426.9 D |
From 46.00€
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