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15-deoxy-Delta12,14-Prostaglandin A2
15-deoxy-Delta12,14-Prostaglandin A2

Item number: Cay10265-500

15-deoxy-Delta12,14-PGA2 is a synthetic analog of PGA2. It shares common structural features with 15-deoxy-Delta12,14-PGJ2, which is a ligand for PPARgamma. Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the biological activity of...
Keywords: 15-deoxy-Delta12,14-PGA2, 9-oxo-prosta-5Z,10,12Z,14E-tetraen-1-oic acid
Application: Bioactive lipid assays
CAS 112839-31-3
MW: 316.4 D
From 98.00€ *
Review
T0070907
T0070907

Item number: Cay10026-5

The peroxisome proliferator-activated receptor-gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARgamma receptor agonists with antidiabetic actions in vivo. There are many PPARgamma...
Keywords: 2-chloro-5-nitro-N-4-pyridinyl-benzamide
Application: PPAR gamma antagonist
CAS 313516-66-4
MW: 277.7 D
From 19.00€ *
Review
13,14-dihydro-15-keto Prostaglandin A2
13,14-dihydro-15-keto Prostaglandin A2

Item number: Cay10260-5

PGE2 is metabolized rapidly to 13,14-dihydro-15-keto PGE2, which is present in the plasma of humans and other mammals. 13,14-dihydro-15-keto PGA2 results from the non-enzymatic dehydration of 13,14-dihydro-15-keto PGE2, a process which is accelerated by the presence of albumin. Further decomposition of...
Keywords: 13,14-dihydro-15-keto PGA2, 9,15-dioxo-prosta-5Z,10-dien-1-oic acid
Application: Bioactive lipid assays
CAS 74872-89-2
MW: 334.5 D
From 119.00€ *
Review