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8-iso Prostaglandin A2
8-iso Prostaglandin A2

Item number: Cay10235-1

8-iso Prostaglandin A2 (8-iso PGA2) is an isoprostane. It is produced by the non-enzymatic oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). 8-iso PGA2 (100 µM) induces calcium influx in HEK293 cells expressing human transient receptor potential ankyrin 1 (TRPA1) and isolated mouse trigeminal...
Keywords: 8-epi PGA2, 9-oxo-15S-hydroxy-(8beta)-prosta-5Z,10,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 474391-66-7
MW: 334.5 D
From 43.00€ *
Review
(S)-AL 8810
(S)-AL 8810

Item number: Cay10023-5

AL 8810 is an 11beta-fluoro analog of PGF2alpha which acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the inverse, (S), or "natural" configuration at C-15 relative to AL 8810, which is 15-(R). The pharmacology of (S)-AL 8810 has not been...
Keywords: 9alpha,15S-dihydroxy-11beta-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid
Application: FP receptor antagonist
CAS 1224444-55-6
MW: 402.5 D
From 81.00€ *
Review