6 products were found matching "Cay10224-%25"!
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trans-EKODE-(E)-Ib
Item number: Cay10004224-25
During oxidative stress, the abundant unsaturated fatty acid linoleic acid undergoes lipid peroxidation to produce alpha,beta-unsaturated epoxy-keto-octadecenoic acids (EKODEs). Nonenzymatic autooxidation of linoleic acid generates six major EKODE isomers, which differ from one another in the positioning and the...
| Keywords: | 12,13-epoxy-9-keto-10(trans)-Octadecenoic Acid, 9-oxo-11-(3-pentyl-2-oxiranyl)-10E-undecenoic acid |
| Application: | Activates an antioxidant response element (ARE) |
| CAS | 478931-82-7 |
| MW: | 310.4 D |
From 66.00€
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MoTP
Item number: Cay15204-25
MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration. MoTP is converted to a cytotoxin in cells with high tyrosinase activity, which in the zebrafish embryo are limited to melanoblasts and newly formed melanocytes....
| Keywords: | 4-(4-Morpholinylbutylthio)phenol, 4-[[4-(4-morpholinyl)butyl]thio]-phenol |
| Application: | Induses melanocyte ablation |
| CAS | 57055-82-0 |
| MW: | 267.4 D |
From 43.00€
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Reversine
Item number: Cay10004412-25
Reversine is a 2,6-disubstituted purine derivative that was originally found to induce dedifferentiation of C2C12 culture myoblast cells into stem cell progenitors when used at a concentration of 5 µM for four days. Depending on cell type, reversine promotes either differentiation or dedifferentiation. For example,...
| Keywords: | N6-cyclohexyl-N2-[4-(4-morpholinyl)phenyl]-9H-purine-2,6-diamine |
| Application: | Control of cell fate |
| CAS | 656820-32-5 |
| MW: | 393.5 D |
From 48.00€
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(±)11(12)-EpETE
Item number: Cay10462-25
Eicosapentaenoic acid (EPA, Cay-90110) is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE (Cay-50861), relaxes vascular and airway smooth muscle by binding large conductance Ca2+-activated K+ (BKCa) channels by...
| Keywords: | (±)11,12-EEQ, (±)11,12-Epoxyeicosatetraenoic Acid, (±)11,12-epoxy-5Z,8Z,14Z,17Z- eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 504435-15-8 |
| MW: | 318.5 D |
From 65.00€
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LP-533401
Item number: Cay10492-25
LP-533401 is an inhibitor of tryptophan 5-hydroxylase 1 (Tph1) that blocks the biosynthesis of gut-derived serotonin, completely inhibiting serotonin production in Tph1-expressing cells at a dose of 1 µM. It prevents the development of and fully rescues, in a dose-dependent manner, osteoporosis in ovariectomized and...
| Keywords: | 4-[2-amino-6-[2,2,2-trifluoro-1-(3'-fluoro[1,1'-biphenyl]-4-yl)ethoxy]-4-pyrimidinyl]-L-phenylalanine |
| Application: | Tph1 inhibitor |
| CAS | 945976-43-2 |
| MW: | 526.5 D |
From 94.00€
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Neurodazine
Item number: Cay13224-50
Neurodazine induces neuronal differentiation in skeletal muscle cells. In mouse C2C12 myoblasts, neurodazine (2 µM for seven days) upregulated the expression of neuron-specific enolase (NSE), neurofilament 200 (NF200), synapsin, and other neuronal markers. Neurodazine similarly upregulated NSE and NF200 in human...
| Keywords: | 2-[5-(3-chlorophenyl)-2-furanyl]-4,5-bis(4-methoxyphenyl)-1H-imidazole |
| Application: | Metabolic studies |
| CAS | 937807-66-4 |
| MW: | 456.9 D |
From 163.00€
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