6 products were found matching "Cay10188"!

trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 µM, respectively)....

Cyclic AMP (cAMP) is an important signal carrier necessary for the proper biological response of cells to hormones, neurotransmitters, and other extracellular signals. Forskolin is a naturally occurring diterpene that is produced by the Indian Coleus plant (C. forskohlii). It directly activates adenylyl cyclase...

Biosynthesis of 20-HETE from arachidonic acid by the cytochrome P450 4A (CYP450 4A) isoforms is an important component of vascular homeostasis, especially in renal circulation. DDMS is a mechanism-based, irreversible inhibitor that has about 10-fold selectivity for the CYP4A2 enzyme which predominantly synthesizes...

Many of the effects of prostaglandin D2 (PGD2) are transduced via a traditional 7-transmembrane GPCR, the DP1 receptor. However, in certain leukocytes and other immune cells, a second PGD2 receptor referred to as the CRTH2 or DP2 receptor has been cloned and characterized. 15(R)-15-methyl PGD2 is a surprisingly...

Immunogen: purified eggshell proteins (Zrp and small amounts of zona pellucida proteins) from Atlantic salmon (S. salar). Clone Designation: MN-7F2. Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 mM sodium azide....

The TP receptor is a G protein-coupled receptor that mediates the action of thromboxane A2 (TXA2). Alternative splicing of TP pre-mRNA produces two receptor variants, TPalpha and TPbeta, which differ in sequence and the length of their carboxy terminal tail. TP receptors are expressed primarily in platelets but are...