- Search results for Cay10165
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6 products were found matching "Cay10165"!
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Item number: Cay10165-10
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 µM, IC50 = 1-5 µM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 µM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 µM. D-erythro-MAPP increases...
Keywords: | (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol,... |
Application: | Ceramide analog |
CAS | 143492-38-0 |
MW: | 361.6 D |
From 15.00€
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Item number: Cay11016-5
A23187 is a calcium ionophore and a microbial metabolite that has been found in S. chartreusensis. It induces calcium overload and mitochondrial apoptosis in HEK293 cells when used at a concentration of 5 µM. A23187 (5 µM) induces the production of reactive oxygen species (ROS) and neutrophil extracellular trap...
Keywords: | Calcimycin,... |
Application: | Cation ionophore |
CAS | 52665-69-7 |
MW: | 523.6 D |
From 50.00€
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Item number: Cay10016-5
Ac-YVAD-CHO is an inhibitor of caspase-1/interleukin-1beta converting enzyme (ICE, Ki = 0.76 nM) and an acetylated form of the caspase-1 inhibitor YVAD-CHO (Cay-27420). It is selective for caspase-1 over caspase-4, -5, -8, -9, and -10 (Kis = 163-970 nM), as well as over caspase-2, -3, -6, and -7 (Kis = >10,000 nM...
Keywords: | N-Ac-Tyr-Val-Ala-Asp-CHO, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxyl-1-formylethyl]-L-alaninamide |
Application: | Caspase-1 inhibitor |
CAS | 143313-51-3 |
MW: | 492.5 D |
From 77.00€
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Item number: Cay10168-5
Arachidonoyl p-nitroaniline (ApNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate...
Keywords: | ApNA, N-(4-nitrophenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | FAAH activity measurement |
CAS | 119520-58-0 |
MW: | 424.6 D |
From 22.00€
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Item number: Cay10162-5
Primary pulmonary hypertension (PPH) is a condition of unknown cause that is characterized by increasing pulmonary arterial and vascular resistance. Treprostinil is a stable analog of prostacyclin (Cay-18220) that is used clinically for the treatment of PPH under the trade name Remodulin(TM). The structural...
Keywords: | BW 15AU, LRX 15, Rumodolin, U-62840, Uniprost,... |
Application: | Prostacyclin analog, prostaglandin I2 receptor agonist |
CAS | 81846-19-7 |
MW: | 390.5 D |
From 130.00€
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Item number: Cay10169-25
Arachidonoyl ethanolamide (AEA, Cay-90050) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (Cay-62160)....
Keywords: | 15(S)-HAEA, 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide |
Application: | Bioactive lipid assays |
CAS | 161744-53-2 |
MW: | 363.5 D |
From 205.00€
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