- Search results for Cay101640-%25
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3 products were found matching "Cay101640-%25"!
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Item number: Cay10640-25
Because selective activation of peripheral cannabinoid (CB2) receptors in rat C-6 glioma cells has been shown to induce apoptosis through enhanced ceramide synthesis de novo, CB2 agonists present potential as anti glioma agents. KM 233 is a Delta8-tetrahydrocannabinol analog with a dimethyl substitution that...
Keywords: | 6aR,7,10,10aR-tetrahydro-6,6,9-trimethyl-3-(1-methyl-1-phenylethyl)-6H-dibenzo[b,d]pyran-1-ol |
Application: | Dual CB1 / CB2 receptor agonist |
CAS | 628263-22-9 |
MW: | 362.5 D |
From 85.00€
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Item number: Cay10460-25
The stress-activated p38 mitogen-activated protein kinase (MAPK) plays a critical role in regulating the production of proinflammatory cytokines such as tumor necrosis factor and interleukin-1. Doramapimod is a highly potent inhibitor of p38 MAPK with a Kd value of 0.1 nM that blocks TNFalpha release in...
Keywords: | BIRB-796, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]-urea |
Application: | p38 MAPK inhibitor |
CAS | 285983-48-4 |
MW: | 527.7 D |
From 35.00€
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Item number: Cay10641-25
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to longevity, cancer, gene regulation, energy homeostasis, and apoptosis. JGB1741 is a small molecule inhibitor of SIRT1 with an IC50 value of 15 µM in a cell-free assay. It shows relatively weak...
Keywords: | ILS-JGB-1741,... |
Application: | SIRT1 inhibitor |
CAS | 1256375-38-8 |
MW: | 440.6 D |
From 86.00€
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