- Search results for Cay10155
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10 products were found matching "Cay10155"!
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Item number: Cay10155-1000
Thromboxane A2 (TXA2) is a potent thrombogenic and vasoconstrictor eicosanoid, produced in large quantities by activated platelets. TXA2 has been implicated as a causal factor in the onset of stroke and myocardial infarction. BM 567 is a dual acting antithrombogenic agent, acting as an inhibitor of thromboxane A2...
Keywords: | 2-(cyclohexylamino)-5-nitro-N-[(pentylamino)carbonyl]-benzenesulfonamide |
Application: | TXA2 synthase inhibitor, TP receptor antagonist |
CAS | 284464-77-3 |
MW: | 412.5 D |
From 82.00€
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Item number: Cay11001-5
(R,S)-Anatabine is an alkaloid that has been found as a minor component in tobacco (Nicotiana). It is an agonist of alpha4beta2 and alpha6/alpha3beta2beta4 subunit-containing nicotinic acetylcholine receptors (nAChRs, EC50s = 6.1 and 3.6 µM, respectively). It is selective for alpha4beta2 and alpha6/alpha3beta2beta4...
Keywords: | 1,2,3,6-tetrahydro-2,3'-bipyridine |
Application: | Amyloid beta production inhibitor |
CAS | 2743-90-0 |
MW: | 160.2 D |
From 50.00€
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Item number: Cay10111-5
rPLA2 is a calcium-dependent cytosolic phospholipase A2 (cPLA2) initially isolated and characterized from bovine and human red blood cells (RBCs). It has a molecular mass of 42 kDa and biochemical properties similar to cPLA2 Type IV. EA4 is a quinone derivative that inhibits rPLA2 with a Ki of 130 µM. It inhibits...
Keywords: | 7-chloro-6-[4-(diethylamino)phenyl]-5,8-quinolinedione |
Application: | cPLA2 inhibitor |
CAS | 389614-94-2 |
MW: | 340.8 D |
From 121.00€
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Item number: Cay11015-500
Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
Keywords: | MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione |
Application: | Synthetic glucocorticoid |
CAS | 50-02-2 |
MW: | 392.5 D |
From 77.00€
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Item number: Cay10115-5
N-Oleoyl dopamine (ODA) is a selective, endogenous vanilloid receptor 1 (VR1) agonist isolated from bovine brain. Structurally, it is the amide of oleic acid and dopamine and is therefore a "hybrid" analog which incorporates components of both the anandamide-like and dopamine neurotransmitter pathways. ODA binds to...
Keywords: | ODA, N-[2-(3,4-dihydroxyphenyl)ethyl]-9Z-octadecenamide |
Application: | VR1 agonist |
CAS | 105955-11-1 |
MW: | 417.6 D |
From 60.00€
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Item number: Cay10156-5
Ramatroban is a dual TP and DP2/CRTH2 receptor antagonist (Kis = 4.5 and 4.3 nM for the human receptors, respectively). It is selective for these receptors over the prostaglandin E2 (PGE2) receptor subtypes EP1 and EP2, as well as the FP and IP receptors, at 1 µM. Ramatroban inhibits contractions induced by U-46619...
Keywords: | Ramatroban, 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid |
Application: | DP2 receptor antagonist |
CAS | 116649-85-5 |
MW: | 416.5 D |
From 43.00€
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Item number: Cay10157-5
APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the...
Keywords: | 2-[6-(4-aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoic acid |
Application: | Detection of radicals |
CAS | 359010-70-1 |
MW: | 423.4 D |
From 204.00€
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Item number: Cay101550-1
The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells. The CB1 and CB2 receptors are G-protein coupled receptors that bind the active component of cannabis, Delta9-tetrahydrocannabinol, as well as anandamide which is an endogenous CB receptor ligand. This...
Keywords: | Anti-CB2, Anti-CX5, Anti-CB2, Anti-CX5, Anti-CNR2, Anti-CB2A, Anti-CB-2, Anti-hCB2, Anti-CB-2, Anti-hCB2, Anti-Cannabinoid... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
456.00€
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Item number: Cay10158-5
Several different arachidonoyl amino acids, including N-arachidonoyl-3-hydroxy-gamma-aminobutyric acid (NAG-3H-ABA), have been isolated and characterized from bovine brain. The glycine congener (NAGly, Cay-90051) was further characterized and found to suppress formalin-induced pain in rats. NAG-3H-ABA was also found...
Keywords: | NAG-3H-ABA, 4-[[(3-hydroxy)-1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]amino]-butanoic acid |
Application: | CB1 receptor ligand |
CAS | 959761-62-7 |
MW: | 405.6 D |
From 22.00€
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Item number: Cay10159-5
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases. There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free...
Keywords: | (2-[6-(4'-hydroxy)phenoxy-3H-xanthene-3-on-9-yl]benzoic acid |
Application: | Detection of radicals |
CAS | 359010-69-8 |
MW: | 424.4 D |
From 222.00€
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