- Search results for Cay10151
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13 products were found matching "Cay10151"!
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Item number: Cay11015-1
Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
Keywords: | MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione |
Application: | Synthetic glucocorticoid |
CAS | 50-02-2 |
MW: | 392.5 D |
From 77.00€
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Item number: Cay10157-1
APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the...
Keywords: | 2-[6-(4-aminophenoxy)-3-oxo-3H-xanthen-9-yl]-benzoic acid |
Application: | Detection of radicals |
CAS | 359010-70-1 |
MW: | 423.4 D |
From 204.00€
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Item number: Cay10156-1
Ramatroban is a dual TP and DP2/CRTH2 receptor antagonist (Kis = 4.5 and 4.3 nM for the human receptors, respectively). It is selective for these receptors over the prostaglandin E2 (PGE2) receptor subtypes EP1 and EP2, as well as the FP and IP receptors, at 1 µM. Ramatroban inhibits contractions induced by U-46619...
Keywords: | Ramatroban, 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid |
Application: | DP2 receptor antagonist |
CAS | 116649-85-5 |
MW: | 416.5 D |
From 43.00€
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Item number: Cay10159-1
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases. There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free...
Keywords: | (2-[6-(4'-hydroxy)phenoxy-3H-xanthene-3-on-9-yl]benzoic acid |
Application: | Detection of radicals |
CAS | 359010-69-8 |
MW: | 424.4 D |
From 222.00€
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Item number: Cay10158-1
Several different arachidonoyl amino acids, including N-arachidonoyl-3-hydroxy-gamma-aminobutyric acid (NAG-3H-ABA), have been isolated and characterized from bovine brain. The glycine congener (NAGly, Cay-90051) was further characterized and found to suppress formalin-induced pain in rats. NAG-3H-ABA was also found...
Keywords: | NAG-3H-ABA, 4-[[(3-hydroxy)-1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl]amino]-butanoic acid |
Application: | CB1 receptor ligand |
CAS | 959761-62-7 |
MW: | 405.6 D |
From 22.00€
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Item number: Cay101500-1
The CB1 receptor and the splice variant CB1a are localized mainly in the brain. The CB1 receptor is a G-protein coupled receptor that binds the active component of cannabis, Delta9-tetrahydrocannabinol. Human and rat CB1 receptors exhibit 97.3% homology at the amino acid level over the complete protein, and 100%...
Keywords: | Anti-CNR, Anti-CB1, Anti-CB1, Anti-CNR1, Anti-CB-R, Anti-CB-R, Anti-CANN6, Anti-CANN6, Anti-Cannabinoid receptor 1,... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
422.00€
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Item number: Cay101550-1
The CB2 receptor is localized predominantly in peripheral tissues, including the spleen and hemopoietic cells. The CB1 and CB2 receptors are G-protein coupled receptors that bind the active component of cannabis, Delta9-tetrahydrocannabinol, as well as anandamide which is an endogenous CB receptor ligand. This...
Keywords: | Anti-CB2, Anti-CX5, Anti-CB2, Anti-CX5, Anti-CNR2, Anti-CB2A, Anti-CB-2, Anti-hCB2, Anti-CB-2, Anti-hCB2, Anti-Cannabinoid... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
456.00€
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Item number: Cay10185-1
4-hydroxy Nonenal is a lipid peroxidation product derived from oxidized omega-6 polyunsaturated fatty acids such as arachidonic acid and linoleic acid. It exhibits various biological activities such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity and has been widely used as a...
Keywords: | 4-ONE, 4-oxo-2E-nonenal |
Application: | Lipid peroxidation marker |
CAS | 103560-62-9 |
MW: | 154.2 D |
From 77.00€
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Item number: Cay10715-1
JWH 018 7-hydroxyindole metabolite-d9 contains nine deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5, and 5 positions. It is intended for use as an internal standard for the quantification of JWH 018 7-hydroxyindole metabolite by GC- or LC-mass spectrometry (MS). JWH 018 7-hydroxyindole metabolite is a minor...
Keywords: | (7-hydroxy-1-pentyl-2,2,3,3,4,4,5,5,5-d9-1H-indol-3-yl)-1-naphthalenyl-methanone |
Application: | Analytical reference standard, GC-MS, LC-MS internal standard, Quantification |
CAS | 2749349-17-3 |
MW: | 366.5 D |
From 339.00€
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Item number: Cay10165-1
D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 µM, IC50 = 1-5 µM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 µM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 µM. D-erythro-MAPP increases...
Keywords: | (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol,... |
Application: | Ceramide analog |
CAS | 143492-38-0 |
MW: | 361.6 D |
From 15.00€
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Item number: Cay10195-1
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of alpha-linolenic acid in the leaves of green plants such as corn. omega-3 and omega-6 polyunsaturated fatty acids in plants are substrates for plant lipoxygenases. 12-oxo PDA is one of the best studied end metabolites of this...
Keywords: | 13-epi-12-oxo PDA, 4-oxo-5R-(2Z)-2-pentenyl-2-cyclopentene-1S-octanoic acid |
Application: | Bioactive lipid assays |
CAS | 71606-07-0 |
MW: | 292.4 D |
From 82.00€
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Item number: Cay10215-1
The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and...
Keywords: | Isopropyl Dodecylfluorophosphonate, P-dodecyl-phosphonofluoridic acid, 1-methylethyl ester |
Application: | MGL inhibitor |
CAS | 615250-02-7 |
MW: | 294.4 D |
From 77.00€
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