3 products were found matching "Cay10146-%25"!
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Leelamine
Item number: Cay10006148-25
Leelamine is a diterpene amine that has been found in gum resin and has diverse biological activities. It inhibits pyruvate dehydrogenase kinase (PDHK, IC50 = 9.5 µM). Leelamine is active against the plant pathogenic fungus B. cinerea (EC50 = 70 µM). It induces apoptosis in UACC-903 and 1205Lu melanoma cell lines...
| Keywords: | Dehydroabietylamine, 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine |
| Application: | PDK inhibitor |
| CAS | 1446-61-3 |
| MW: | 285.5 D |
From 50.00€
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JGB1741
Item number: Cay10641-25
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to longevity, cancer, gene regulation, energy homeostasis, and apoptosis. JGB1741 is a small molecule inhibitor of SIRT1 with an IC50 value of 15 µM in a cell-free assay. It shows relatively weak...
| Keywords: | ILS-JGB-1741,... |
| Application: | SIRT1 inhibitor |
| CAS | 1256375-38-8 |
| MW: | 440.6 D |
From 86.00€
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Paclitaxel
Item number: Cay10461-25
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values...
| Keywords: | NSC 125973, betaS-(benzoylamino)-alphaR-hydroxy-benzenepropanoic acid,... |
| Application: | Apotosis inducer |
| CAS | 33069-62-4 |
| MW: | 853.9 D |
From 43.00€
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