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12-Lipoxygenase (platelet-type, mouse recombinant)
Item number: Cay10341-25
12-Lipoxygenase (12-LO) catalyzes the formation of 12-HpETE from arachidonic acid. There are two main types of 12-LO, platelet-type and leukocyte-type, which share only 60% identity at the amino acid level and strongly differ in substrate specificity and enzyme kinetics. Leukocyte-type 12-LO has the ability to also...
| Keywords: | Alox12, P-12LO, P-12LO, Alox12p, 12S-LOX, 12S-LOX, 12S-lipoxygenase, 12S-lipoxygenase, Lipoxin synthase 12-LO, Lipoxin... |
| Application: | Enzyme activity |
| MW: | 76,4 kD |
489.00€
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JGB1741
Item number: Cay10641-25
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to longevity, cancer, gene regulation, energy homeostasis, and apoptosis. JGB1741 is a small molecule inhibitor of SIRT1 with an IC50 value of 15 µM in a cell-free assay. It shows relatively weak...
| Keywords: | ILS-JGB-1741,... |
| Application: | SIRT1 inhibitor |
| CAS | 1256375-38-8 |
| MW: | 440.6 D |
From 86.00€
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