7 products were found matching "Cay10129-%25"!

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15(S)-HETE Ethanolamide
15(S)-HETE Ethanolamide

Item number: Cay10169-25

Arachidonoyl ethanolamide (AEA, Cay-90050) was the first endogenous cannabinoid (CB) to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as THC. Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (Cay-62160)....
Keywords: 15(S)-HAEA, 15(S)-hydroxy-N-(2-hydroxyethyl)-5Z,8Z,11Z,13E-eicosatetraenamide
Application: Bioactive lipid assays
CAS 161744-53-2
MW: 363.5 D
From 205.00€ *
Review
Emodin
Emodin

Item number: Cay13109-25

Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 µM)....
Keywords: Archin, Frangulic Acid, NSC 408120, NSC 622947, Schuttgelb, 1,3,8-trihydroxy-6-methyl-9,10-anthracenedione
Application: CK2 inhibitor
CAS 518-82-1
MW: 270.2 D
From 40.00€ *
Review
TIC10
TIC10

Item number: Cay16109-25

TIC10 induces the expression of TNF-related apoptosis-inducing ligand (TRAIL) at 1-5 µM in a p53-independent manner. It is orally active, stable, and crosses the blood-brain barrier. The induction of TRAIL results from dual inhibition of Akt and ERK1/2 combined with nuclear translocation of the transcription factor...
Keywords: ONC201, 2,4,6,7,8,9-hexahydro-4-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one
Application: TRAIL expression inducer
CAS 1616632-77-9
MW: 386.5 D
From 43.00€ *
Review
N-Octadecyl-N'-propyl-sulfamide
N-Octadecyl-N'-propyl-sulfamide

Item number: Cay10009661-25

Peroxisome proliferator-activated receptors (PPARs) play an essential role in regulating lipid and glucose metabolism. Oleoyl ethanolamide (OEA), a natural ligand for PPARalpha, has been shown to suppress food intake and reduce weight gain in rats when administered systemically at 10 mg/kg intraperitoneally....
Keywords: N-octadecyl-N'-propyl-sulfamide
Application: PPARalpha activator
CAS 925891-74-3
MW: 390.7 D
From 102.00€ *
Review
PtdIns-(3,4,5)-P3-biotin (sodium salt)
PtdIns-(3,4,5)-P3-biotin (sodium salt)

Item number: Cay10009531-25

The PtdIn phosphates play an important role in the generation and transduction of intracellular signals. PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any...
Keywords: Phosphatidylinositol-3,4,5-triphosphate C-8-biotin, PIP3-biotin,...
Application: Affinity probe
CAS 1415684-80-8
MW: 1155.8 D
From 212.00€ *
Review
20-hydroxy N-Arachidonoyl Taurine
20-hydroxy N-Arachidonoyl Taurine

Item number: Cay10009501-25

Arachidonic acid is metabolized by cytochrome P450 (CYP450) 4A omega-hydroxylase to 20-HETE, which acts as a vasoconstrictor in the kidney and brain. During mass spectrometry lipidomics analysis of rat brain, a series of fatty acyl amides of taurine was discovered, of which arachidonoyl taurine is a prominent...
Keywords: 20-hydroxy-2-[(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)amino]-ethane sulfonic acid
Application: Bioactive lipid assays
MW: 427.6 D
From 195.00€ *
Review
2-thio-Acetyl MAGE
2-thio-Acetyl MAGE

Item number: Cay10009651-25

KIAA1363 is a recently characterized 2-acetyl monoacylglyceryl ether hydrolase that is critical to the survival and proliferation of many cancer cell lines. 2-thioacetyl MAGE is a colorimetric substrate for KIAA1363. It can readily be adapted to perform activity/inhibition studies of this new enzyme, using standard...
Keywords: S-[2-(hexadecyloxy)-1-(hydroxymethyl)ethyl]ester, ethanethioic acid
Application: Bioactive lipid assays
CAS 112014-15-0
MW: 374.6 D
From 53.00€ *
Review