6 products were found matching "Cay10065"!
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15-deoxy-Delta12,14-Prostaglandin A1
Item number: Cay10065-500
15-deoxy-Delta12,14-Prostaglandin A1 (15-deoxy-Delta12,14-PGA1) is a synthetic PGA1 analog. It shares common structural features with 15-deoxy-Delta12,14-PGJ2, which is a ligand for PPARgamma. Antimitotic and antitumor activity have been reported for a similar analog, but there are no published reports on the...
| Keywords: | 15-deoxy-Delta12,14-PGA1, 9-oxo-prosta-10,12Z,14E-trien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 573951-20-9 |
| MW: | 318.5 D |
From 129.00€
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Nifedipine
Item number: Cay11106-5
Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 µM. Nifedipine (1 µM) reduces TGF-beta-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse...
| Keywords: | BAY 1040, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3,5-dimethyl ester |
| Application: | Dihydropyridine calcium channel blocker |
| CAS | 21829-25-4 |
| MW: | 346.3 D |
From 27.00€
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CAY10665
Item number: Cay11044-500
Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA). In this model, the omega-3 PUFA eicosapentaenoic acid (EPA, 3-10 µM) reduces the contraction rate of cells, indicating a positive antiarrhythmic effect....
| Keywords: | 16-[[2-(methylamino)-2-oxoacetyl]amino]-11Z-hexadecenoic acid |
| Application: | 17,18-EET analog |
| CAS | 1235543-17-5 |
| MW: | 354.5 D |
From 65.00€
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Onalespib
Item number: Cay10655-1
Onalespib is a selective inhibitor of Hsp90 (IC50 = 18 nM). It induces the degradation of specific Hsp90 client proteins, including mutant EGFR, for up to seven days in tumor cell lines in vitro and up to three days in vivo. Onalespib is retained in tumor xenografts and is efficacious in a range of xenograft...
| Keywords: | AT-13387, [1,3-dihydro-5-[(4-methyl-1-piperazinyl)methyl]-2H-isoindol-2-yl][2,4-dihydroxy-5-(1-methylethyl)phenyl]-methanone |
| Application: | Antineoplastic, Hsp90 inhibitor |
| CAS | 912999-49-6 |
| MW: | 409.5 D |
From 60.00€
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Indole-3-thio Carboxamide
Item number: Cay11065-500
Indole-3-thio Carboxamide is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 1H-indole-3-carbothioamide. CAS Number: 59108-90-6. Molecular Formula: C9H8N2S. Formula Weight: 176.2. Purity: >97%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml,...
| Keywords: | 1H-indole-3-carbothioamide |
| Application: | Synthetic intermediate |
| CAS | 59108-90-6 |
| MW: | 176.2 D |
From 125.00€
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URB597
Item number: Cay10046-5
URB597 is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme that hydrolyzes anandamide (AEA, Cay-90050) and other simple esters and amides with long unsaturated acyl chains (IC50 = 4.6 nM and 0.5 nM in brain membranes and intact neurons, respectively). URB597 exhibits both...
| Keywords: | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl)-cyclohexylcarbamate |
| Application: | FAAH inhibitor |
| CAS | 546141-08-6 |
| MW: | 338.4 D |
From 54.00€
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