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Item number: Cay11044-25

Isolated neonatal rat cardiomyocytes, which spontaneously beat in culture, are used to evaluate the antiarrhythmic effects of polyunsaturated fatty acids (PUFA). In this model, the omega-3 PUFA eicosapentaenoic acid (EPA, 3-10 µM) reduces the contraction rate of cells, indicating a positive antiarrhythmic effect....

Keywords:	16-[[2-(methylamino)-2-oxoacetyl]amino]-11Z-hexadecenoic acid
Application:	17,18-EET analog
CAS	1235543-17-5
MW:	354.5 D

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CAY10444

Item number: Cay10005033-25

CAY10444 is a sphingosine-1-phosphate receptor 3 (S1P3) antagonist. It inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 (IC50 = 11.6 µM). CAY10444 (5 µM) inhibits S1P-induced growth and migration of MH7A rheumatoid fibroblast-like synoviocyte cells. It inhibits the localization and...

Keywords:	BML-241, 2-undecyl-thiazolidine-4-carboxylic acid
Application:	S1P3 receptor antagonist
CAS	298186-80-8
MW:	287.5 D

From 73.00€ *

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