- Search results for Cay10035
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10 products were found matching "Cay10035"!
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Item number: Cay10035-1
8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane. It inhibits aldo-keto reductase family 1 member B10 (AKR1B10) in COS-7 lysates expressing the human enzyme when used at a concentration of 60 µM. 8-iso PGA1 (0.1 µM) inhibits potassium-induced D-aspartate release from isolated bovine retinas.Formal Name:...
Keywords: | 8-epi PGA1, 8-iso PGA1, 9-oxo-15S-hydroxy-(8beta)-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 211186-29-7 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay11033-5
PRMT4/CARM1 Inhibitor selectively blocks the activity of PRMT4/CARM1 with an IC50 value of 7.1 µM. It displays very low affinity towards PRMT1 and SET7 with IC50 values of 63 and 943 µM, respectively. In human prostate cancer LNCaP cells, this compound reduced the prostate-specific antigen promoter activity at 8-10...
Keywords: | Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1 Inhibitor,... |
CAS | 1020399-49-8 |
MW: | 555.3 D |
From 109.00€
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Item number: Cay100035-1
Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-Arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase (HSL) to mobilize...
Keywords: | Anti-MGL, Anti-MGL, Anti-MAGL, Anti-MAGL, Anti-HU-K5, Anti-HU-K5, Anti-Monoglyceride lipase, Anti-Monoglyceride lipase,... |
Application: | IHC (paraffin), WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay11035-10
Aminoindans (AI) were originally studied as semi-rigid congeners of phenylethylamines, which are psychoactive alkaloids. 5-IAI is a psychoactive analog of p-iodoamphetamine and is indistinguishable, in its physiological effects, from 3,4-methylenedioxymethamphetamine in rats. A single 40 mg/kg dose of 5-IAI...
Keywords: | 5-iodo-2-Aminoindane, 2,3-dihydro-5-iodo-1H-inden-2-amine, monohydrochloride |
Application: | Analytical reference standard, Psychoactive p-iodoamphetamine analog |
CAS | 1782044-60-3 |
MW: | 295.6 D |
From 109.00€
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Item number: Cay10335-100
Methylation of lysine residues in core histones plays a critical role in regulating gene expression. Jumonji domain containing 2D (JMJD2D) catalyzes the demethylation of di- and tri-methylated forms of histone H3 at lysine residue 9 (me 2/3), leading to transcriptional repression and activation, respectively. Like...
Keywords: | KDM4D, JHDM3D, Lysine-specific demethylase 4D, Lysine-specific demethylase 4D, Jumonji domain-containing protein 2D,... |
Application: | Enzyme activity |
MW: | 42,7 kD |
642.00€
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Item number: Cay10031-5
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at...
Keywords: | 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine |
Application: | Bioactive lipid assays |
CAS | 121324-31-0 |
MW: | 593.7 D |
From 126.00€
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Item number: Cay10032-5
Certain chronic neurologic disorders, such as Parkinson's disease, are caused by an insufficiency of the neurotransmitter dopamine secondary to the degeneration of substantia nigra dopaminergic neurons. N-(alpha-Linolenoyl) tyrosine (NALT) is a simple alpha-amide conjugate between the omega-3 essential fatty acid...
Keywords: | NALT, N-(L-tyrosine)-9Z,12Z,15Z-octadecatrienamide |
Application: | Increases CNS dopamine levels |
CAS | 259143-19-6 |
MW: | 441.6 D |
From 96.00€
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Item number: Cay10039-5
FR122047 is a selective inhibitor of COX-1. The IC50 values for inhibition of human COX-1 and COX-2 are 0.028 and 65 µM, respectively. In human platelet-rich plasma, FR122047 inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation with an IC50 of 180-200 nM, which is nearly 100 times more potent...
Keywords: | 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride |
Application: | COX-1 inhibitor |
CAS | 130717-51-0 |
MW: | 460 D |
From 43.00€
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Item number: Cay10038-5
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...
Keywords: | 2,3',4,5'-Tetramethoxystilbene, 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene |
Application: | CYP1B1 inhibitor |
CAS | 24144-92-1 |
MW: | 300.4 D |
From 22.00€
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Item number: Cay10033-25
Lipoxin A4 (LXA4) methyl ester is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes. LXA4 is equipotent to leukotriene B4 (LTB4) in inducing...
Keywords: | 5(S),6(R),15(S)-TriHETE methyl ester, LXA4 methyl ester, 5S,6R,15S-trihydroxy-7E,9E,11Z,13E-eicosatetraenoic acid, methyl... |
Application: | Bioactive lipid assays |
CAS | 97643-35-1 |
MW: | 366.5 D |
From 368.00€
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