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POV-PC
POV-PC

Item number: Cay10031-25

Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at...
Keywords: 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine
Application: Bioactive lipid assays
CAS 121324-31-0
MW: 593.7 D
From 126.00€ *
Review
6-ECDCA
6-ECDCA

Item number: Cay11031-25

Farnesoid X receptor (FXR) is a nuclear receptor that is activated by bile acid, with chenodeoxycholic acid (CDCA) being a representative natural ligand. 6-ECDCA is a synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 = 99 nM). Through FXR, it alters gene expression that results in...
Keywords: INT 747, Obeticholic Acid, (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid
Application: FXR agonist
CAS 459789-99-2
MW: 420.6 D
From 135.00€ *
Review