- Search results for Cay10031
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10 products were found matching "Cay10031"!
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Item number: Cay10031-1
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at...
Keywords: | 2-(5-oxovaleryl) Phosphatidylcholine, 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphatidylcholine |
Application: | Bioactive lipid assays |
CAS | 121324-31-0 |
MW: | 593.7 D |
From 126.00€
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Item number: Cay11003-1
RORgamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis...
Keywords: | NR1F3, RAR-Related Orphan Receptor C, Retinoid-Related Orphan Receptor gamma |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
369.00€
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Item number: Cay11033-1
PRMT4/CARM1 Inhibitor selectively blocks the activity of PRMT4/CARM1 with an IC50 value of 7.1 µM. It displays very low affinity towards PRMT1 and SET7 with IC50 values of 63 and 943 µM, respectively. In human prostate cancer LNCaP cells, this compound reduced the prostate-specific antigen promoter activity at 8-10...
Keywords: | Protein Arginine Methyltransferase 4/Coactivator-Associated Arginine Methyltransferase 1 Inhibitor,... |
CAS | 1020399-49-8 |
MW: | 555.3 D |
From 109.00€
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Item number: Cay10003-1
This mixture contains the characteristic metabolites of both PGI2 and TXA2. Contents: Thromboxane B2, 11-dehydro Thromboxane B2, 6-keto Prostaglandin F1alpha, 2,3-dinor-6-keto Prostaglandin F1alpha (100 µg each), and 12(S)-HHTrE (5 µg).Purity: >98% for each compound. Formulation: (Request formulation change), A...
Application: | Control |
130.00€
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Item number: Cay10311-100
(R)-(-)-Mellein is a dihydroisocoumarin compound produced by A. ochraceus Wilhelm. It has a variety of biological activities including antibacterial, antimalarial, antifungal, and anticancer effects. (R)-(-)-Mellein inhibits proliferation of human breast cancer (MCF-7 and MDA-MB-468) and melanoma (SK-MEL-28 and...
Keywords: | Ochracin, 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one |
Application: | Proliferation inhibitor |
CAS | 480-33-1 |
MW: | 178.2 D |
From 68.00€
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Item number: Cay11031-5
Farnesoid X receptor (FXR) is a nuclear receptor that is activated by bile acid, with chenodeoxycholic acid (CDCA) being a representative natural ligand. 6-ECDCA is a synthetic bile acid that acts as a potent and selective agonist of FXR (EC50 = 99 nM). Through FXR, it alters gene expression that results in...
Keywords: | INT 747, Obeticholic Acid, (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxy-cholan-24-oic acid |
Application: | FXR agonist |
CAS | 459789-99-2 |
MW: | 420.6 D |
From 135.00€
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Item number: Cay10035-1
8-iso Prostaglandin A1 (8-iso PGA1) is an isoprostane. It inhibits aldo-keto reductase family 1 member B10 (AKR1B10) in COS-7 lysates expressing the human enzyme when used at a concentration of 60 µM. 8-iso PGA1 (0.1 µM) inhibits potassium-induced D-aspartate release from isolated bovine retinas.Formal Name:...
Keywords: | 8-epi PGA1, 8-iso PGA1, 9-oxo-15S-hydroxy-(8beta)-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 211186-29-7 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10037-1
10-Nitrolinoleate is a nitrated fatty acid and a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist. It is formed from linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) upon exposure to acidified nitrite.Formal Name: 10-nitro-9E,12Z-octadecadienoic acid. CAS Number: 774603-04-2. Synonyms: 10-LNO2,...
Keywords: | 10-nitro-9,12-Octadecadienoic Acid, LNO2, 10-nitro-9E,12Z-octadecadienoic acid |
Application: | PPAR gamma activator |
CAS | 774603-04-2 |
MW: | 325.4 D |
From 65.00€
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Item number: Cay10038-1
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...
Keywords: | 2,3',4,5'-Tetramethoxystilbene, 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene |
Application: | CYP1B1 inhibitor |
CAS | 24144-92-1 |
MW: | 300.4 D |
From 22.00€
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Item number: Cay10039-1
FR122047 is a selective inhibitor of COX-1. The IC50 values for inhibition of human COX-1 and COX-2 are 0.028 and 65 µM, respectively. In human platelet-rich plasma, FR122047 inhibits arachidonic acid, collagen, and ADP-induced platelet aggregation with an IC50 of 180-200 nM, which is nearly 100 times more potent...
Keywords: | 1-[[4,5-bis(4-methoxyphenyl)-2-thiazolyl]carbonyl]-4-methyl-piperazine, monohydrochloride |
Application: | COX-1 inhibitor |
CAS | 130717-51-0 |
MW: | 460 D |
From 43.00€
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