7 products were found matching "Cay10020-%25"!
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Genipin
Item number: Cay10010622-25
Uncoupling protein 2 (UCP2) is a mitochondrial carrier protein that is expressed in pancreatic islets and has been shown to negatively regulate glucose-stimulated insulin secretion. High levels of UCP2 expression can disrupt pancreatic beta cell function and downregulate insulin secretion thereby contributing to the...
| Keywords: | (+)-Genipin, 1R,4aS,5,7aS-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid, methyl ester |
| Application: | UCP2 inhibitor |
| CAS | 6902-77-8 |
| MW: | 226.2 D |
From 24.00€
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CAY10565
Item number: Cay10010528-25
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO)....
| Keywords: | 4-(p-methoxyphenyl)-1,3,2-Oxathiazolylium-5-olate, 4-methoxy-4-phenyl-1,3,2-oxathiazolidine-5-one |
| Application: | NO donor |
| MW: | 211.2 D |
From 43.00€
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CAY10563
Item number: Cay10010526-25
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO)....
| Keywords: | 4-(p-trifluoromethylphenyl)-1,3,2-Oxathiazolylium-5-olate, 4-trifluoro-4-phenyl-1,3,2-oxathiazolidine-5-one |
| Application: | NO donor |
| MW: | 249.2 D |
From 43.00€
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U-46619 Glycine methyl ester
Item number: Cay10010522-25
U-46619 is a stable analog of the endoperoxide PGH2, and a TP receptor agonist. It exhibits properties similar to TXA2, causing platelet shape change, aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0, and 7.3 nM respectively,...
| Keywords: | 9,11-dideoxy-9alpha,11alpha-methanoepoxy-prosta-5Z,13E-dien-1-oic acid, methyl ester |
| Application: | Bioactive lipid assays |
| MW: | 421.6 D |
From 56.00€
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Suc-Leu-Tyr-AMC
Item number: Cay10008120-25
The calpains are a family of calcium-dependent cysteine proteases, with calpain I (µ-calpain) requiring micromolar calcium and calpain II (m-calpain) requiring millimolar calcium. Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the...
| Keywords: | Suc-LY-AMC, N-(3-carboxy-1-oxopropyl)-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-tyrosinamide |
| Application: | Fluorescent calpain I & II & papain & 20S proteasome substrate |
| CAS | 94367-20-1 |
| MW: | 551.6 D |
From 50.00€
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Valdecoxib
Item number: Cay10006120-25
Valdecoxib is a selective inhibitor of COX-2 (IC50s = 0.005 and 140 µM for human recombinant COX-2 and COX-1, respectively). It decreases LPS-induced production of prostaglandin E2 (PGE2, Cay-14010) in isolated human whole blood (IC50 = 0.89 µM). Valdecoxib reduces carrageenan-induced paw edema and adjuvant-induced...
| Keywords: | SC-65872, 4-(5-methyl-3-phenyl-4-isoxazolyl)-benzenesulfonamide |
| Application: | COX-2 inhibitor |
| CAS | 181695-72-7 |
| MW: | 314.4 D |
From 97.00€
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4-hydroxy Tolbutamide
Item number: Cay10008520-25
4-hydroxy Tolbutamide is a metabolite of the potassium channel antagonist tolbutamide (Cay-19888). It is formed from tolbutamide by the cytochrome P450 (CYP) isoform CYP2C9 in human liver microsomes and COS-7 cell lysates expressing the human enzyme. 4-hydroxy Tolbutamide has been used as a marker of CYP2C9 activity...
| Keywords: | N-[(butylamino)carbonyl]-4-(hydroxymethyl)-benzenesulfonamide |
| Application: | Bioactive lipid assays |
| CAS | 5719-85-7 |
| MW: | 286.4 D |
From 56.00€
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