- Search results for Cay10020
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9 products were found matching "Cay10020"!
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Item number: Cay10020-5
Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility. Prostaglandins of the A-series are natural products of gorgonian soft coral. PGA1 has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. There...
Keywords: | PGA1 ethyl ester, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid, ethyl ester |
Application: | Bioactive lipid assays |
CAS | 93464-24-5 |
MW: | 364.5 D |
From 90.00€
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Item number: Cay11020-1
Bisindolylmaleimide II (BIM II) is a general inhibitor of all protein kinase C (PKC) subtypes with structural similarity to the nonspecific PKC inhibitor staurosporine. At 10 µM, BIM II inhibits 98% of PKCalpha kinase activity. Additionally, it inhibits PDK1 (IC50 = 14 µM), an important kinase in the insulin...
Keywords: | BIM II, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione |
Application: | PKC inhibitor |
CAS | 137592-45-1 |
MW: | 438.5 D |
From 77.00€
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Item number: Cay100020-500
Immunogen: purified eggshell proteins (Zrp and small amounts of zona pellucida proteins) from Atlantic salmon (S. salar). Clone Designation: MN-2B4. Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 mM sodium azide....
Application: | WB, ELISA |
Host: | Mouse |
Species reactivity: | atlantic salmon |
From 385.00€
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Item number: Cay10026-10
The peroxisome proliferator-activated receptor-gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARgamma receptor agonists with antidiabetic actions in vivo. There are many PPARgamma...
Keywords: | 2-chloro-5-nitro-N-4-pyridinyl-benzamide |
Application: | PPAR gamma antagonist |
CAS | 313516-66-4 |
MW: | 277.7 D |
From 19.00€
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Item number: Cay10029-50
MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...
Keywords: | L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic... |
Application: | CysLT1 receptor antagonist |
CAS | 115104-28-4 |
MW: | 515.1 D |
From 43.00€
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Item number: Cay10023-10
AL 8810 is an 11beta-fluoro analog of PGF2alpha which acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the inverse, (S), or "natural" configuration at C-15 relative to AL 8810, which is 15-(R). The pharmacology of (S)-AL 8810 has not been...
Keywords: | 9alpha,15S-dihydroxy-11beta-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid |
Application: | FP receptor antagonist |
CAS | 1224444-55-6 |
MW: | 402.5 D |
From 81.00€
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Item number: Cay10022-50
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
Application: | Antitumor agent, Apoptosis inducer |
CAS | 36098-33-6 |
MW: | 362.2 D |
From 19.00€
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Item number: Cay10028-10
Pioglitazone is an agonist of the peroxisome proliferator-activated receptor gamma (PPARgamma, EC50 = ~500-600 nM for both human and murine PPARgamma). It is selective for PPARgamma over PPARalpha, exhibiting low level activation of PPARalpha at 1 µM and 5.4-fold activation at a concentration of 10 µM. Pioglitazone...
Keywords: | 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, monopotassium salt |
Application: | PPARgamma agonist |
CAS | 1266523-09-4 |
MW: | 394.5 D |
From 39.00€
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Item number: Cay10021-10
Clioquinol is a metal-chelating antimicrobial agent with neuroprotective properties. It inhibits the growth of A. fumigatus with MIC values of 1, >32, 8, and 16 µg/ml in media containing no metal, iron, zinc, and copper, respectively. Clioquinol (37 mg/kg) decreases neuronal loss in the substantia nigra pars...
Keywords: | Iodochlorohydroxyquin, NSC 3531, NSC 74938, 5-chloro-7-iodo-8-quinolinol |
Application: | Antifungal, Amebicide, Metal-chelating antimicrobial agent, Neuroprotective agent |
CAS | 130-26-7 |
MW: | 305.5 D |
From 34.00€
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