9 products were found matching "Cay10020"!

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Prostaglandin A1 ethyl ester
Prostaglandin A1 ethyl ester

Item number: Cay10020-5

Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility. Prostaglandins of the A-series are natural products of gorgonian soft coral. PGA1 has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. There...
Keywords: PGA1 ethyl ester, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid, ethyl ester
Application: Bioactive lipid assays
CAS 93464-24-5
MW: 364.5 D
From 90.00€ *
Review
Bisindolylmaleimide II
Bisindolylmaleimide II

Item number: Cay11020-1

Bisindolylmaleimide II (BIM II) is a general inhibitor of all protein kinase C (PKC) subtypes with structural similarity to the nonspecific PKC inhibitor staurosporine. At 10 µM, BIM II inhibits 98% of PKCalpha kinase activity. Additionally, it inhibits PDK1 (IC50 = 14 µM), an important kinase in the insulin...
Keywords: BIM II, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione
Application: PKC inhibitor
CAS 137592-45-1
MW: 438.5 D
From 77.00€ *
Review
Anti-Zona Radiata (salmon)   (Clone MN-2B4)
Anti-Zona Radiata (salmon) (Clone MN-2B4)

Item number: Cay100020-500

Immunogen: purified eggshell proteins (Zrp and small amounts of zona pellucida proteins) from Atlantic salmon (S. salar). Clone Designation: MN-2B4. Formulation: (Request formulation change), Affinity-purified IgG in 0.1 M sodium phosphate, pH 7.4, containing 0.15 M sodium chloride, 1% BSA, and 12.3 mM sodium azide....
Application: WB, ELISA
Host: Mouse
Species reactivity: atlantic salmon
From 385.00€ *
Review
T0070907
T0070907

Item number: Cay10026-10

The peroxisome proliferator-activated receptor-gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARgamma receptor agonists with antidiabetic actions in vivo. There are many PPARgamma...
Keywords: 2-chloro-5-nitro-N-4-pyridinyl-benzamide
Application: PPAR gamma antagonist
CAS 313516-66-4
MW: 277.7 D
From 19.00€ *
Review
MK-571
MK-571

Item number: Cay10029-50

MK-571 is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes). It inhibits contractions induced by leukotriene D4 (LTD4, Cay-20310) or LTE4 (Cay-20410) in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1,...
Keywords: L-660,711, (E)-3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic...
Application: CysLT1 receptor antagonist
CAS 115104-28-4
MW: 515.1 D
From 43.00€ *
Review
(S)-AL 8810
(S)-AL 8810

Item number: Cay10023-10

AL 8810 is an 11beta-fluoro analog of PGF2alpha which acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the inverse, (S), or "natural" configuration at C-15 relative to AL 8810, which is 15-(R). The pharmacology of (S)-AL 8810 has not been...
Keywords: 9alpha,15S-dihydroxy-11beta-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid
Application: FP receptor antagonist
CAS 1224444-55-6
MW: 402.5 D
From 81.00€ *
Review
F16
F16

Item number: Cay10022-50

F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
Keywords: 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide
Application: Antitumor agent, Apoptosis inducer
CAS 36098-33-6
MW: 362.2 D
From 19.00€ *
Review
Pioglitazone (potassium salt)
Pioglitazone (potassium salt)

Item number: Cay10028-10

Pioglitazone is an agonist of the peroxisome proliferator-activated receptor gamma (PPARgamma, EC50 = ~500-600 nM for both human and murine PPARgamma). It is selective for PPARgamma over PPARalpha, exhibiting low level activation of PPARalpha at 1 µM and 5.4-fold activation at a concentration of 10 µM. Pioglitazone...
Keywords: 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, monopotassium salt
Application: PPARgamma agonist
CAS 1266523-09-4
MW: 394.5 D
From 39.00€ *
Review
Clioquinol
Clioquinol

Item number: Cay10021-10

Clioquinol is a metal-chelating antimicrobial agent with neuroprotective properties. It inhibits the growth of A. fumigatus with MIC values of 1, >32, 8, and 16 µg/ml in media containing no metal, iron, zinc, and copper, respectively. Clioquinol (37 mg/kg) decreases neuronal loss in the substantia nigra pars...
Keywords: Iodochlorohydroxyquin, NSC 3531, NSC 74938, 5-chloro-7-iodo-8-quinolinol
Application: Antifungal, Amebicide, Metal-chelating antimicrobial agent, Neuroprotective agent
CAS 130-26-7
MW: 305.5 D
From 34.00€ *
Review