6 products were found matching "Cay10013-%25"!
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MK-886 (sodium salt)
Item number: Cay10133-25
Arachidonic acid (Cay-90010) and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). The intervention of a second protein, 5-LO-activating protein (FLAP), is required before 5-LO can become catalytically active. MK-886...
| Keywords: | 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)-1H-indole-2-propanoic acid,... |
| Application: | Leukotriene biosynthesis inhibitor |
| CAS | 118427-55-7 |
| MW: | 494.1 D |
From 43.00€
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Pravastatin (sodium salt)
Item number: Cay10010343-25
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the "statin" class of cholesterol-lowering drugs. Pravastatin is a HMG-CoA reductase inhibitor that is a ring hydroxylated metabolite of mevastatin. It is a competitive inhibitor...
| Keywords: | 1S,2S,6S,7S,8R,8aR-hexahydro-betaR,deltaR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid,... |
| Application: | Potent HMG-CoA reductase inhibitor |
| CAS | 81131-70-6 |
| MW: | 446.5 D |
From 35.00€
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WWL70
Item number: Cay10011213-25
WWL70 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 70 nM). It increases the expression of the adipose browning-related gene Ucp1 in differentiated 3T3-L1 mouse adipocytes and increases the oxygen consumption rate (OCR), an effect that can be blocked by the PPARalpha antagonist...
| Keywords: | N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester |
| Application: | ABHD6 inhibitor |
| CAS | 947669-91-2 |
| MW: | 437.5 D |
From 61.00€
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AG-99
Item number: Cay10010313-25
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
| Keywords: | Tyrphostin 46, Tyrphostin AG-99, 2-cyano-3-(3,4-dihydroxyphenyl)-2E-propenamide |
| Application: | EGF receptor kinase inhibitor |
| CAS | 122520-85-8 |
| MW: | 204.2 D |
From 46.00€
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PtdIns-(3,4,5)-P3-fluorescein (triethylammonium salt)
Item number: Cay10010383-25
The phosphatidylinositols (PtdIns) phosphates represent a small precentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(4,5)-P2 can be phosphorylated by phosphatidylinositol (PI)-3-kinase to make PtdIns-(3,4,5)-P3, which initiates...
| Keywords: | 1-(1-octadecanoyl-fluorescein-2R-octanoylphosphatidyl)inositol-3,4,5-trisphosphate, heptatriethylammonium salt |
| Application: | Bioactive lipid assays |
| MW: | 1908.2 D |
From 115.00€
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N-cis-hexadec-9Z-enoyl-L-Homoserine lactone
Item number: Cay10012673-25
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
| Keywords: | C16:1-Delta9-(L)-HSL, N-(2-oxotetrahydrofuran-3S-yl) Palmitoleyl Amide,... |
| Application: | Antibiotic |
| CAS | 479050-94-7 |
| MW: | 337.5 D |
From 60.00€
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