- Search results for Cay10012567-%25
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6 products were found matching "Cay10012567-%25"!
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Item number: Cay10012562-25
Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for...
Keywords: | 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-pyridazine |
Application: | SCD inhibitor |
CAS | 944808-88-2 |
MW: | 389.8 D |
From 106.00€
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Item number: Cay10012565-25
Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. Selective analgesia through TRPV1-mediated entry of a cationic lidocaine derivative, QX314, was recently reported. CAY10568 is a physically smaller, less hydrophobic version of QX314...
Keywords: | Santinamide, trimethyl[(phenylcarbamoyl)methyl]-ammonium iodide |
Application: | Metabolic studies |
CAS | 22913-17-3 |
MW: | 320.2 D |
From 50.00€
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Item number: Cay10012597-25
Xanthine oxidoreductase mediates the successive oxidation of hypoxanthine and xanthine to produce uric acid. The enzyme can interconvert between xanthine dehydrogenase and xanthine oxidase activities through reversible sulfhydryl oxidation on specific cysteine residues. Both forms oxidize hypoxanthine and xanthine...
Keywords: | 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one |
CAS | 315-30-0 |
MW: | 136.1 D |
43.00€
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Item number: Cay10012577-25
Hydrogen sulfide (H2S) is an endogenously-produced gaseous second messenger that can regulate many physiological processes. Diallyl trisulfide (DATS) is an organic polysulfide compound found in garlic that acts as an H2S donor. It reduces the survival of prostate cancer PC-3 cells (IC50 = 22 µM) and inhibits the...
Keywords: | DATS, NSC 651936, di-2-propen-1-yl trisulfide |
Application: | Natural H2S donor, bioactive organic polysulfide compound |
CAS | 2050-87-5 |
MW: | 178.3 D |
From 53.00€
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Item number: Cay10010502-25
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO)....
Keywords: | 4-phenyl-1,3,2-Oxathiazolylium-5-olate, 4-phenyl-1,3,2-oxathiazolidine-5-one |
Application: | NO donor |
MW: | 181.2 D |
From 43.00€
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Item number: Cay10010267-25
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
Keywords: | 4-amino-[2,3'-bithiophene]-5-carboxamide |
Application: | IKK2 inhibitor |
CAS | 354812-17-2 |
MW: | 224.3 D |
From 60.00€
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