- Search results for Cay10012539-%25
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4 products were found matching "Cay10012539-%25"!
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Item number: Cay10012539-5
The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on Th2 cells, eosinophils, and basophils where it mediates the chemotactic activity of PGD2. CAY10597, as a racemic mixture, is...
Keywords: | 5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'-pyrrolidine-1(2H)-acetic acid |
Application: | CRTH2receptor antagonist, DP2 receptor antagonist |
CAS | 916046-55-4 |
MW: | 416.8 D |
From 96.00€
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Item number: Cay10539-100
Very long chain polyunsaturated fatty acids (VLCPUFAs) are important components of ceramides and sphingomyelin and are present in retina, sperm, and brain. Tetratriaconta-16(Z),19(Z),22(Z),25(Z),28(Z),31(Z)-hexaenoic acid is a C34:6 VLCPUFA whose specific biological actions are largely unknown. This VLCPUFA, along...
Keywords: | 16Z,19Z,22Z,25Z,28Z,31Z-tetratriacontahexaenoic acid |
Application: | Bioactive Lipid Assays |
CAS | 105528-06-1 |
MW: | 496.8 D |
From 125.00€
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Item number: Cay10010239-25
The development of selective, cell-permeable protein kinase inhibitors for the treatment of cancer, inflammation, and other diseases, is a major focus of drug development efforts. Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta...
Keywords: | 9-Bromopaullone, NSC 664704, 9-bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
Application: | CDK inhibitor, GSK-3 beta inhibitor |
CAS | 142273-20-9 |
MW: | 327.2 D |
From 66.00€
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Item number: Cay10010339-25
Lovastatin hydroxy acid is a potent and competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM). It is the more potent, open ring, hydroxy acid form of its prodrug, lovastatin (Cay-10010338).Formal Name:...
Keywords: | 2-methyl-1S,2,3R,7S,8S,8aR-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthal... |
Application: | NF-kappaB activation inhibitor |
CAS | 75225-50-2 |
MW: | 444.5 D |
From 50.00€
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