- Search results for Cay10011566
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4 products were found matching "Cay10011566"!
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Item number: Cay10011566-96
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. SIRT3 is a mitochondrial protein that plays a role in metabolic regulation and other cellular...
Keywords: | SIRT3, hSIRT3, SIR2L3, EC=3.5.1.-, SIR2-like protein 3, NAD-dependent deacetylase sirtuin-3, mitochondrial |
Application: | SIRT3 activator/inhibitor screening |
Species reactivity: | human |
467.00€
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Item number: Cay10156-5
Ramatroban is a dual TP and DP2/CRTH2 receptor antagonist (Kis = 4.5 and 4.3 nM for the human receptors, respectively). It is selective for these receptors over the prostaglandin E2 (PGE2) receptor subtypes EP1 and EP2, as well as the FP and IP receptors, at 1 µM. Ramatroban inhibits contractions induced by U-46619...
Keywords: | Ramatroban, 3R-[[(4-fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid |
Application: | DP2 receptor antagonist |
CAS | 116649-85-5 |
MW: | 416.5 D |
From 43.00€
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Item number: Cay10011563-96
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Transcriptional...
Keywords: | Histone Deacetylase |
Application: | HDAC activity measurement |
436.00€
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Item number: Cay10011564-96
Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Changes in the...
Keywords: | Histone Deacetylase 1 |
Application: | HDAC1 inhibitor screening |
Species reactivity: | human |
467.00€
*