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Item number: Cay10011564-96

Histone deacetylases (HDACs) catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation of DNA to be relaxed and transcriptional activation to ensue. Changes in the...

Keywords:	Histone Deacetylase 1
Application:	HDAC1 inhibitor screening
Species reactivity:	human

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