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Item number: Cay11500-25

ABT-263 is an inhibitor of the Bcl-2 family proteins Bcl-2, Bcl-xL, and Bcl-W (Kis = is = 550 and 354 nM, respectively). ABT-263 is cytotoxic in a panel of small cell lung cancer (SCLC), leukemia, and lymphoma cell lines with a mean EC50 value of 1 µM. It induces apoptosis in influenza A-infected retinal pigment...

Keywords:	A-855071, Navitoclax,...
Application:	Potent, cell-permeable BH3 domain mimetic
CAS	923564-51-6
MW:	974.6 D

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