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Steviol
Steviol

Item number: Cay10011344-25

Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...
Keywords: Hydroxy Dehydrostevic Acid, NSC 226902, (4alpha)-13-hydroxy-kaur-16-en-18-oic acid
Application: OAT1 / OAT3 inhibitor
CAS 471-80-7
MW: 318.5 D
From 115.00€ *
Review
CAY10441
CAY10441

Item number: Cay10005186-25

CAY10441 is an antagonist of the IP receptor. It is selective for the IP receptor over the prostaglandin E2 (PGE2) receptor subtypes EP1, EP2, EP3, and EP4, the FP and TP receptors, and a panel of 30 other receptors and ion channels but does bind to the alpha2A-adrenergic and imidazoline I2 receptors. CAY10441...
Keywords: RO1138452, 4,5-dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imadazol-2-amine
Application: cAMP blocker
CAS 221529-58-4
MW: 309.4 D
From 201.00€ *
Review
CAY10444
CAY10444

Item number: Cay10005033-25

CAY10444 is a sphingosine-1-phosphate receptor 3 (S1P3) antagonist. It inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 (IC50 = 11.6 µM). CAY10444 (5 µM) inhibits S1P-induced growth and migration of MH7A rheumatoid fibroblast-like synoviocyte cells. It inhibits the localization and...
Keywords: BML-241, 2-undecyl-thiazolidine-4-carboxylic acid
Application: S1P3 receptor antagonist
CAS 298186-80-8
MW: 287.5 D
From 73.00€ *
Review