4 products were found matching "Cay10011343-%25"!

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Steviol
Steviol

Item number: Cay10011344-25

Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...
Keywords: Hydroxy Dehydrostevic Acid, NSC 226902, (4alpha)-13-hydroxy-kaur-16-en-18-oic acid
Application: OAT1 / OAT3 inhibitor
CAS 471-80-7
MW: 318.5 D
From 115.00€ *
Review
Dimebolin (hydrochloride)
Dimebolin (hydrochloride)

Item number: Cay10011349-25

Dimebolin is a neuroprotective agent. It binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as alpha1A-, alpha1B-, alpha1D-, and alpha2A-adrenergic receptors (ARs), imidazoline I2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 8-313...
Keywords: Dimebon, Latrepirdine, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole,...
Application: Neuroprotective agent
CAS 97657-92-6
MW: 392.4 D
From 31.00€ *
Review
Anti-Hsf1   (Clone 10H8)
Anti-Hsf1 (Clone 10H8)

Item number: Cay10011433-25

Heat shock factor 1 (Hsf1) belongs to a family of heat shock transcription factors that activate the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function. The up-regulation of Hsp expression by stressors is achieved at the level of transcription...
Keywords: Heat Shock Factor 1
Application: WB, IP, ICC, EIA
Host: Rat
Species reactivity: human, mouse, rat, bovine, hamster, monkey, rabbit
From 163.00€ *
Review
Pravastatin (sodium salt)
Pravastatin (sodium salt)

Item number: Cay10010343-25

Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the "statin" class of cholesterol-lowering drugs. Pravastatin is a HMG-CoA reductase inhibitor that is a ring hydroxylated metabolite of mevastatin. It is a competitive inhibitor...
Keywords: 1S,2S,6S,7S,8R,8aR-hexahydro-betaR,deltaR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid,...
Application: Potent HMG-CoA reductase inhibitor
CAS 81131-70-6
MW: 446.5 D
From 35.00€ *
Review