13 products were found matching "Cay10011343"!

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Pravastatin (sodium salt)
Pravastatin (sodium salt)

Item number: Cay10010343-10

Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the "statin" class of cholesterol-lowering drugs. Pravastatin is a HMG-CoA reductase inhibitor that is a ring hydroxylated metabolite of mevastatin. It is a competitive inhibitor...
Keywords: 1S,2S,6S,7S,8R,8aR-hexahydro-betaR,deltaR,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid,...
Application: Potent HMG-CoA reductase inhibitor
CAS 81131-70-6
MW: 446.5 D
From 35.00€ *
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Anti-Hsf1   (Clone 10H8)
Anti-Hsf1 (Clone 10H8)

Item number: Cay10011433-25

Heat shock factor 1 (Hsf1) belongs to a family of heat shock transcription factors that activate the transcription of genes encoding products required for protein folding, processing, targeting, degradation, and function. The up-regulation of Hsp expression by stressors is achieved at the level of transcription...
Keywords: Heat Shock Factor 1
Application: WB, IP, ICC, EIA
Host: Rat
Species reactivity: human, mouse, rat, bovine, hamster, monkey, rabbit
From 163.00€ *
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Steviol
Steviol

Item number: Cay10011344-10

Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...
Keywords: Hydroxy Dehydrostevic Acid, NSC 226902, (4alpha)-13-hydroxy-kaur-16-en-18-oic acid
Application: OAT1 / OAT3 inhibitor
CAS 471-80-7
MW: 318.5 D
From 115.00€ *
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Glycerophospho-N-Arachidonoyl Ethanolamine
Glycerophospho-N-Arachidonoyl Ethanolamine

Item number: Cay10011347-1

N-Acylated ethanolamines (NAE) are naturally-occurring lipids that have diverse bioactivities. The different types of NAE can be derived from glycerophospho-linked precursors by the activity of glycerophosphodiesterase 1 (GDE1). Glycerophospho-N-arachidonoyl ethanolamine is the precursor of arachidonoyl ethanolamide...
Keywords: Glycerophospho-Arachidonoyl Ethanolamide, Glycerophosphoanandamide, GP-NArE,...
Application: Bioactive lipid assays
CAS 201738-25-2
MW: 501.6 D
From 113.00€ *
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Dimebolin (hydrochloride)
Dimebolin (hydrochloride)

Item number: Cay10011349-5

Dimebolin is a neuroprotective agent. It binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as alpha1A-, alpha1B-, alpha1D-, and alpha2A-adrenergic receptors (ARs), imidazoline I2 receptors, and the serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 8-313...
Keywords: Dimebon, Latrepirdine, 2,3,4,5-tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-1H-pyrido[4,3-b]indole,...
Application: Neuroprotective agent
CAS 97657-92-6
MW: 392.4 D
From 31.00€ *
Review
Taprostene (free acid)
Taprostene (free acid)

Item number: Cay10011348-5

Taprostene is a stable prostacyclin (PGI2) analog and agonist of the prostacyclin receptor, IP. It does not activate the PGE2 receptor EP4, which, like IP, promotes vascular smooth muscle relaxation when stimulated. Taprostene has been used extensively to study the role of the IP receptor in tissue preparations and...
Keywords: CG 4203, Rheocyclan,...
Application: PGI2 analog
CAS 108945-35-3
MW: 398.5 D
From 123.00€ *
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Oligomycin B
Oligomycin B

Item number: Cay11343-10

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin B is a nonselective inhibitor of the mitochondrial F1FO ATP synthase. Oligomycin B (1-10 µM) can reduce the rate...
Keywords: (1S,2'R,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,28R,29S)-22-ethyl-5',6'-dihydro-7,11,14,15-tetrahydrox...
Application: Apoptosis inducer
CAS 11050-94-5
MW: 805.1 D
From 54.00€ *
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Anti-IgG1 Isotype Control FITC   (Clone MOPC-21)
Anti-IgG1 Isotype Control FITC (Clone MOPC-21)

Item number: Cay10343-100

The IgG1 isotype control FITC is fluorescein conjugated non-specific mouse IgG1 produced from hybridoma clone MOPC-21. This conjugate should be used as a control antibody in direct fluorescence immunostaining experiments which utilize a mouse IgG1-fluorescein conjugate as the primary antibody.Synonyms: IgG1kappa...
Keywords: IgG1kappa Fluorescein Isotype Control, IgG1kappa Isotype Control FITC
Application: FC, IFM
Host: Mouse
205.00€ *
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Prostaglandin A1-biotin
Prostaglandin A1-biotin

Item number: Cay10013-100

Prostaglandin A1 (PGA1) is one of the cyclopentenone prostaglandins, which have well documented antimitotic and antiproliferative effects. The activity of the compounds in this class, which includes prostaglandins in both the A- and J-series, may result from changes in gene expression and the interaction with...
Keywords: PGA1-biotin, N-9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oyl-N'-biotinoyl-1,6-diaminopentane
Application: Affinity probe
MW: 646.9 D
From 44.00€ *
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MG Acidic Solution
MG Acidic Solution

Item number: Cay10011143-1

Formulation: 600 µl of a solution containing ammonium molybdate and sulfuric acid.
Application: Kit component
32.00€ *
Review
Anti-LAMP1   (Clone Ly1C6)
Anti-LAMP1 (Clone Ly1C6)

Item number: Cay10011443-100

Lysosome-associated membrane protein 1 (LAMP-1), also known as CD107a, is an abundant lysosomal integral membrane glycoprotein. It is composed of a signal peptide, two LAMP-like domains that are separated by a proline-rich hinge region, a transmembrane domain, and a C-terminal tail that contains a YXXI...
Keywords: Lysosome Associated Membrane Protein 1
Application: WB, IP, ICC
Host: Mouse
Species reactivity: rat
From 324.00€ *
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Cysteinyl Leukotriene Express AChE Tracer
Cysteinyl Leukotriene Express AChE Tracer

Item number: Cay10011323-500

Synonyms: CysLT Express AChE Tracer. Formulation: A lyophilized powder. Origin: Animal/Eel.
Keywords: CysLT Express AChE Tracer
Application: Tracer
From 291.00€ *
Review
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