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(±)-Rolipram
(±)-Rolipram

Item number: Cay10011132-25

Type 4 cyclic nucleotide phosphodiesterases (PDE4) isoforms selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP. (±)-Rolipram is a cell-permeable selective PDE4 inhibitor. Since PDE4 is abundant in leukocytes, (±)-rolipram inhibits inflammation by suppressing...
Keywords: SB 95952, ZK 62711, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
Application: PDE4 inhibitor
CAS 61413-54-5
MW: 275.3 D
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