4 products were found matching "Cay10011263-%25"!

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CAY10578
CAY10578

Item number: Cay10011264-25

Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an...
Keywords: 4,5,6,7-tetraiodo-1,3-dioxo-2-isoindolineacetic acid
Application: CK2 inhibitor
CAS 19231-60-8
MW: 708.8 D
From 24.00€ *
Review
14,15-Leukotriene E4
14,15-Leukotriene E4

Item number: Cay10011362-25

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the...
Keywords: 14,15-LTE4, Eoxin E4, EXE4, 15S-hydroxy-14R-(S-cysteinyl)-5Z,8Z,10E,12E-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 1000852-57-2
MW: 439.6 D
From 177.00€ *
Review
N-dodecanoyl-L-Homoserine lactone
N-dodecanoyl-L-Homoserine lactone

Item number: Cay10011203-25

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...
Keywords: C12-HSL, dDHL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-dodecanamide
Application: Antibiotic
CAS 137173-46-7
MW: 283.4 D
From 60.00€ *
Review
WWL70
WWL70

Item number: Cay10011213-25

WWL70 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 70 nM). It increases the expression of the adipose browning-related gene Ucp1 in differentiated 3T3-L1 mouse adipocytes and increases the oxygen consumption rate (OCR), an effect that can be blocked by the PPARalpha antagonist...
Keywords: N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester
Application: ABHD6 inhibitor
CAS 947669-91-2
MW: 437.5 D
From 61.00€ *
Review