- Search results for Cay10011256-%25
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7 products were found matching "Cay10011256-%25"!
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Item number: Cay10011250-25
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM. NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM. In mammalian cells, NH125...
Keywords: | 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide |
Application: | eEF-2K inhibitor |
CAS | 278603-08-0 |
MW: | 524.6 D |
From 54.00€
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Item number: Cay10011251-25
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by a number of extracellular stimuli such as insulin, growth factors, cell specification factors, and cell adhesion. Its activity regulates many cell functions including cell division, apoptosis, and inflammation. TWS119 is a...
Keywords: | 3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]-phenol |
Application: | GSK3beta inhibitor |
CAS | 601514-19-6 |
MW: | 318.3 D |
From 50.00€
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Item number: Cay10011286-25
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid. It is formed from cholesterol in the liver via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. CDCA is a farnesoid X receptor (FXR) agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and...
Keywords: | Anthropodeoxycholic Acid, CDCA, Fluibil, Hekbilin, Kebilis, Ulmenide, (3alpha,5beta,7alpha)-3,7-dihydroxy-cholan-24-oic acid |
Application: | Bioactive lipid assays |
CAS | 474-25-9 |
MW: | 392.6 D |
From 43.00€
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Item number: Cay10011206-25
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | 3-oxo-C8-HSL, N-beta-oxo-octanoyl-L-Homoserine lactone, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide |
Application: | Antibiotic |
CAS | 147795-39-9 |
MW: | 241.3 D |
From 52.00€
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Item number: Cay10011246-25
Janus kinase 3 (JAK3) is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STATs). JAK3 is abundantly expressed in normal lymphoid cells as well as human...
Keywords: | Janex 1, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
Application: | JAK3 inhibitor |
CAS | 202475-60-3 |
MW: | 297.3 D |
From 42.00€
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Item number: Cay10011296-25
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism. They are also inherently cytotoxic, as physiological...
Keywords: | pregna-4-17(20)-diene-3,16-dione |
Application: | FXR antagonist |
CAS | 39025-24-6 |
MW: | 312.5 D |
From 50.00€
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Item number: Cay10011126-25
Clobenpropit is a selective histamine H3 receptor antagonist (Ki = 0.17 nM in rat cortical membranes). Clobenpropit (0.3, 0.1, and 3 nM) reduces inhibition of electrically induced contractions in isolated guinea pig ileum longitudinal muscle by the H3 receptor agonist (R)-alpha-methylhistamine (Cay-25601). It does...
Keywords: | VUF 9153, N-[(4-chlorophenyl)methyl]-carbamimidothioic acid, 3-(1H-imidazol-5-yl)propyl ester, dihydrobromide |
Application: | Histamine H3 receptor antagonist |
CAS | 145231-35-2 |
MW: | 470.7 D |
From 50.00€
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