- Search results for Cay10011236
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15 products were found matching "Cay10011236"!
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Item number: Cay10011362-25
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the...
Keywords: | 14,15-LTE4, Eoxin E4, EXE4, 15S-hydroxy-14R-(S-cysteinyl)-5Z,8Z,10E,12E-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 1000852-57-2 |
MW: | 439.6 D |
From 177.00€
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Item number: Cay10011263-100
Two types of 15-lipoxygenase (15-LO) have been discovered and characterized, both of which metabolize arachidonic acid (AA) to produce 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE). 15-LO-1 oxygenates AA at both C-15 and C-12, whereas 15-LO-2 exclusively oxygenates C-15 of AA. Human 15-LO-2 has a molecular mass of...
Keywords: | 15-LOX-B, 15-LOX-B, Arachidonate 15-lipoxygenase B, Arachidonate 15-lipoxygenase B, Linoleate 13-lipoxygenase 15-LOb,... |
Application: | Enzyme activity |
MW: | 76 kD |
642.00€
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Item number: Cay10010236-10
ML-9 was originally identified as a selective Ca2+-calmodulin-dependent myosin light chain kinase inhibitor. Concentrations from 10-100 µM are effective at inhibiting vascular smooth muscle tension and reducing intracellular Ca2+ concentrations. ML-9 also inhibits PKB/Akt activity with an IC50 range of 10-50 µM in...
Keywords: | 1-[(5-chloro-1-naphthalenyl)sulfonyl]hexahydro-1H-1,4-diazepine, monohydrochloride |
Application: | Ser/Thr kinase inhibitor |
CAS | 105637-50-1 |
MW: | 361.3 D |
From 77.00€
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Item number: Cay10011237-10
Reversible protein phosphorylation is a fundamental regulatory mechanism in all aspects of biology. Protein phosphatase 2A (PP2A) is a divalent cation-independent protein serine/threonine phosphatase involved in regulating numerous cellular processes including the cell cycle, growth and differentiation and is also...
Keywords: | RP-C, RP-C, PPP2CA, PP2A-alpha, PP2A-alpha, Replication protein C, Replication protein C, Serine/threonine-protein... |
Application: | Enzyme activity |
MW: | 38,6 kD |
385.00€
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Item number: Cay10011238-1
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | 3-oxo-C16:1-Delta11cis-(L)-HSL, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-(11Z)-hexadecenamide |
Application: | Bioactive lipid assays |
CAS | 1269663-80-0 |
MW: | 351.5 D |
From 40.00€
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Item number: Cay10011231-1
Origin: Animal/Goat.
Application: | Kit component |
Host: | Goat |
Species reactivity: | rabbit |
98.00€
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Item number: Cay10011234-1
Formulation: 1 mg/ml in PBS, pH 7.4, 250 µl per vial.
Application: | Kit component |
98.00€
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Item number: Cay10011286-1
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid. It is formed from cholesterol in the liver via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. CDCA is a farnesoid X receptor (FXR) agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and...
Keywords: | Anthropodeoxycholic Acid, CDCA, Fluibil, Hekbilin, Kebilis, Ulmenide, (3alpha,5beta,7alpha)-3,7-dihydroxy-cholan-24-oic acid |
Application: | Bioactive lipid assays |
CAS | 474-25-9 |
MW: | 392.6 D |
From 43.00€
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Item number: Cay10011206-5
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: | 3-oxo-C8-HSL, N-beta-oxo-octanoyl-L-Homoserine lactone, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octanamide |
Application: | Antibiotic |
CAS | 147795-39-9 |
MW: | 241.3 D |
From 52.00€
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Item number: Cay10011246-5
Janus kinase 3 (JAK3) is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STATs). JAK3 is abundantly expressed in normal lymphoid cells as well as human...
Keywords: | Janex 1, 4-[(6,7-dimethoxy-4-quinazolinyl)amino]-phenol |
Application: | JAK3 inhibitor |
CAS | 202475-60-3 |
MW: | 297.3 D |
From 42.00€
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Item number: Cay10011296-1
Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism. They are also inherently cytotoxic, as physiological...
Keywords: | pregna-4-17(20)-diene-3,16-dione |
Application: | FXR antagonist |
CAS | 39025-24-6 |
MW: | 312.5 D |
From 50.00€
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Item number: Cay10011256-5
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis and its activity is increased in many proliferating tissues and tumors, which lends promise as an anti-cancer drug target. CAY10577 inhibits CK2 with an...
Keywords: | 7,8-dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
Application: | CK2 inhibitor |
CAS | 300675-28-9 |
MW: | 258.1 D |
From 24.00€
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