Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators...

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is involved in a promising field of study. The expression of specific target genes, such as transcriptional...

N-hexanoyl-DL-Homoserine lactone is a bacterial quorum sensing signaling molecule that is produced by mammalian pathogenic and rhizosphere-colonizing bacteria. Application of N-hexanoyl-DL-homoserine lactone (60 µM) to tomato leaves suppresses the development of lesions induced by the plant pathogenic fungi B....

Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in...

Deoxynojirimycin (dNM) tetrabenzyl ether is an intermediate for the synthesis of glucosylceramide synthase inhibitors such as 1-dNM, a glucose analog that potently inhibits alpha-glucosidase I and II.Formal Name: 3R,4R,5S-tris(phenylmethoxy-2R-[(phenylmethoxy)methyl]-piperidine. CAS Number: 69567-11-9. Synonyms: DNJ...