3 products were found matching "Cay10011135-%25"!
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ICI 192605
Item number: Cay10135-25
ICI 192605 is a potent antagonist of the thromboxane A2 receptor (TP) that blocks contraction of isolated guinea pig trachea induced by U-46619 (Cay-16450, Kd = 0.398 nM). It is used to study the role of TP signaling in tissues and animals.Formal Name:...
| Keywords: | (4Z)-rel-6-[(2R,4R,5S)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]-4-hexenoic acid |
| Application: | Thromboxane A2 receptor antagonist |
| CAS | 117621-64-4 |
| MW: | 402.9 D |
From 43.00€
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(±)-Rolipram
Item number: Cay10011132-25
Type 4 cyclic nucleotide phosphodiesterases (PDE4) isoforms selectively inactivate the second messenger cAMP by hydrolyzing the phosphodiester bond, producing AMP. (±)-Rolipram is a cell-permeable selective PDE4 inhibitor. Since PDE4 is abundant in leukocytes, (±)-rolipram inhibits inflammation by suppressing...
| Keywords: | SB 95952, ZK 62711, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
| Application: | PDE4 inhibitor |
| CAS | 61413-54-5 |
| MW: | 275.3 D |
From 39.00€
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BAY 41-8543
Item number: Cay10011131-25
Soluble guanylate cyclase (sGC) is the primary cellular receptor for nitric oxide (NO). NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cyclic GMP (cGMP). BAY 41-8543 is a heme-dependent stimulator of sGC, increasing the activity of recombinant sGC...
| Keywords: | 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine |
| Application: | SGC stimulator |
| CAS | 256498-66-5 |
| MW: | 420.4 D |
From 44.00€
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