- Search results for Cay10011131
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8 products were found matching "Cay10011131"!
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Item number: Cay10011131-10
Soluble guanylate cyclase (sGC) is the primary cellular receptor for nitric oxide (NO). NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cyclic GMP (cGMP). BAY 41-8543 is a heme-dependent stimulator of sGC, increasing the activity of recombinant sGC...
Keywords: | 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine |
Application: | SGC stimulator |
CAS | 256498-66-5 |
MW: | 420.4 D |
From 44.00€
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Item number: Cay10133-1
Arachidonic acid (Cay-90010) and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). The intervention of a second protein, 5-LO-activating protein (FLAP), is required before 5-LO can become catalytically active. MK-886...
Keywords: | 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)-1H-indole-2-propanoic acid,... |
Application: | Leukotriene biosynthesis inhibitor |
CAS | 118427-55-7 |
MW: | 494.1 D |
From 43.00€
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Item number: Cay10013-1
Prostaglandin A1 (PGA1) is one of the cyclopentenone prostaglandins, which have well documented antimitotic and antiproliferative effects. The activity of the compounds in this class, which includes prostaglandins in both the A- and J-series, may result from changes in gene expression and the interaction with...
Keywords: | PGA1-biotin, N-9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oyl-N'-biotinoyl-1,6-diaminopentane |
Application: | Affinity probe |
MW: | 646.9 D |
From 44.00€
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Item number: Cay10113-1
AL 8810 (Cay-16735) is an 11beta-fluoro analog of prostaglandin F2alpha (Cay-16010) which acts as a potent and selective antagonist at the FP receptor. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as...
Keywords: | 9alpha,15R-dihydroxy-11beta-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid,... |
Application: | FP receptor antagonist |
CAS | 208114-93-6 |
MW: | 444.6 D |
From 105.00€
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Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
Application: | PDE2 inhibitor |
CAS | 439083-90-6 |
MW: | 476.6 D |
From 125.00€
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Item number: Cay10131-1
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain. It activates liver X receptors (LXRs) in the developing ventral midbrain to induce stem cell differentiation into dopaminergic neurons. 24(S),25-epoxy Cholesterol inhibits IL-6 production and degranulation of bone...
Keywords: | 24(S)-24,25-EC, (3beta,24S)-24,25-epoxy-cholest-5-en-3-ol |
Application: | Oxysterol, LXR activator |
CAS | 77058-74-3 |
MW: | 400.6 D |
271.00€
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Item number: Cay10011213-1
WWL70 is an inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50 = 70 nM). It increases the expression of the adipose browning-related gene Ucp1 in differentiated 3T3-L1 mouse adipocytes and increases the oxygen consumption rate (OCR), an effect that can be blocked by the PPARalpha antagonist...
Keywords: | N-methyl-N-[[3-(4-pyridinyl)phenyl]methyl]-carbamic acid, 4'-(aminocarbonyl)[1,1'-biphenyl]-4-yl ester |
Application: | ABHD6 inhibitor |
CAS | 947669-91-2 |
MW: | 437.5 D |
From 61.00€
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Item number: Cay10011143-1
Formulation: 600 µl of a solution containing ammonium molybdate and sulfuric acid.
Application: | Kit component |
32.00€
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