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QX-314 (bromide)
QX-314 (bromide)

Item number: Cay10011032-25

QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 µM capsaicin, a TRPV1 receptor agonist, 5 mM...
Keywords: 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-ethanaminium bromide
Application: Sodium channel blocker
CAS 24003-58-5
MW: 343.3 D
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