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KT 5823
Item number: Cay10010965-100
The activity of cGMP-dependent protein kinase (PKG) is controlled by factors that elevate cellular cGMP, like nitric oxide (NO), and by those that reduce cGMP levels, like certain phosphodiesterases. KT 5823 is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50 = 234 nM). KT 5823 is...
| Keywords: | 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]b... |
| Application: | PKG inhibitor |
| CAS | 126643-37-6 |
| MW: | 495.5 D |
From 50.00€
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CAY10535
Item number: Cay10010396-5
TPalpha and TPbeta are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPbeta is believed to be responsible for vascular endothelial growth factor-induced...
| Keywords: | N-(tert-butylcarbamoyl)-2-(3-methoxyphenoxy)-5-nitrobenzenesulfonamide |
| Application: | TP receptor antagonist |
| CAS | 945716-28-9 |
| MW: | 423.4 D |
From 48.00€
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