- Search results for Cay10010723-%25
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7 products were found matching "Cay10010723-%25"!
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Item number: Cay10010337-25
Fluvastatin is an inhibitor of HMG-CoA reductase (Ki = 0.3 nM for the rat enzyme). It also inhibits the human cytochrome P450 (CYP) isoform CYP2C9 (IC50 = 100 nM). Fluvastatin inhibits oxidized LDL-induced ferroptosis and reverses oxidized LDL-induced decreases in glutathione peroxidase 4 (GPX4) and system Xc-...
Keywords: | 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid, sodium salt, hydrate |
Application: | Hydroxymethylglutaryl-coenzyme A reductase inhibitor |
MW: | 410.5 D |
From 35.00€
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Item number: Cay10010637-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific...
Keywords: | 17R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
Application: | Bioactive lipid assays |
CAS | 183509-24-2 |
MW: | 320.5 D |
From 196.00€
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Item number: Cay10010367-25
The Ras/Raf-1 signalling pathway is a well-characterized system that links receptor tyrosine kinase (RTK) activation with changes in gene expression and cell behavior. Raf-1 is a serine/threonine protein kinase that phosphorylates and activates MAPK-kinase (MEK) in response to activation by Ras. ZM 336372 is a...
Keywords: | 3-(dimethylamino)-N-[3-[(4-hydroxybenzoyl)amino]-4-methylphenyl]-benzamide |
Application: | Raf-1 inhibitor |
CAS | 208260-29-1 |
MW: | 389.4 D |
From 58.00€
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Item number: Cay10010173-25
(S)-Equol is an agonist of estrogen receptor alpha (ERalpha) and ERbeta and an active metabolite of the polyketide isoflavone daidzein (Cay-10005166). It is formed from daidzein by gut microbiota. (S)-Equol induces ERalpha-and ERbeta-mediated gene transcription in HEC-1 cells expressing the human receptors in a...
Keywords: | (-)-Equol, 4',7-Dihydroxyisoflavan, 4',7-Isoflavandiol, (S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol |
Application: | ERbeta agonist |
CAS | 531-95-3 |
MW: | 242.3 D |
From 28.00€
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Item number: Cay10010372-25
GW 842166X is a cannabinoid 2 (CB2) receptor agonist. It increases intracellular calcium mobilization induced by the CB receptor agonist CP 55,940 (Cay-13241) in HEK cells co-expressing a chimeric Galphaq/05 protein and the human CB2 receptor (EC50 = 7.78 µM). GW 842166X is selective for CB2 over the CB1 receptor...
Keywords: | 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro-2H-pyran-4-yl)methyl]-4-(trifluoromethyl)-5-pyrimidinecarboxamide |
Application: | CB2 receptor agonist |
CAS | 666260-75-9 |
MW: | 449.3 D |
From 30.00€
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Item number: Cay10010123-25
Prostaglandin D2-d9 (PGD2-d9) is intended for use as an internal standard for the quantification of PGD2 (Cay-12010) by GC- or LC-MS. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of...
Keywords: | PGD2-d9, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid |
Application: | Standard |
MW: | 361.5 D |
From 106.00€
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Item number: Cay10007103-25
3-thio-Pheneacrylic acid is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 3-(3-thienyl)-2-propenoic acid. CAS Number: 1195-52-4. Synonyms: 3-Thiophen-3-yl-Acrylic Acid. Molecular Formula: C7H6O2S. Formula Weight: 154.2. Purity: >98%. Formulation: (Request formulation change), A...
Keywords: | 3-Thiophen-3-yl-Acrylic Acid, 3-(3-thienyl)-2-propenoic acid |
Application: | Synthetic intermediate, Pharmaceutical synthesis |
CAS | 1195-52-4 |
MW: | 154.2 D |
From 26.00€
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