3 products were found matching "Cay10010624-%25"!
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Genipin
Item number: Cay10010622-25
Uncoupling protein 2 (UCP2) is a mitochondrial carrier protein that is expressed in pancreatic islets and has been shown to negatively regulate glucose-stimulated insulin secretion. High levels of UCP2 expression can disrupt pancreatic beta cell function and downregulate insulin secretion thereby contributing to the...
| Keywords: | (+)-Genipin, 1R,4aS,5,7aS-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid, methyl ester |
| Application: | UCP2 inhibitor |
| CAS | 6902-77-8 |
| MW: | 226.2 D |
From 24.00€
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SP600125
Item number: Cay10010466-25
SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
| Keywords: | 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one |
| Application: | JNK inhibitor |
| CAS | 129-56-6 |
| MW: | 220.2 D |
From 60.00€
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14,15-EE-8(Z)-E
Item number: Cay10010486-25
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator...
| Keywords: | 14,15-Epoxyeicosa-8(Z)-enoic Acid, 13[(2R,3S)-3-pentyloxiranyl]-8Z-tridecenoic acid |
| Application: | Vasodilator agonist |
| CAS | 519038-93-8 |
| MW: | 324.5 D |
From 65.00€
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