7 products were found matching "Cay10010623-%25"!
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Genipin
Item number: Cay10010622-25
Uncoupling protein 2 (UCP2) is a mitochondrial carrier protein that is expressed in pancreatic islets and has been shown to negatively regulate glucose-stimulated insulin secretion. High levels of UCP2 expression can disrupt pancreatic beta cell function and downregulate insulin secretion thereby contributing to the...
| Keywords: | (+)-Genipin, 1R,4aS,5,7aS-tetrahydro-1-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid, methyl ester |
| Application: | UCP2 inhibitor |
| CAS | 6902-77-8 |
| MW: | 226.2 D |
From 24.00€
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Latrunculin A
Item number: Cay10010630-25
Actin disruption is used to study cell functions in vitro (e.g., migration, endocytosis) and in vivo (e.g., tumor cell invasion). Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can...
| Keywords: | NSC 613011,... |
| Application: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421.6 D |
From 66.00€
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(±)18-HETE
Item number: Cay10010638-25
(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has...
| Keywords: | (±)18-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 133268-58-3 |
| MW: | 320.5 D |
From 196.00€
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(±)16-HETE
Item number: Cay10010635-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE...
| Keywords: | (±)16-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 128914-46-5 |
| MW: | 320.5 D |
From 196.00€
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(±)17-HETE
Item number: Cay10010636-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 µM the (S)-enantiomer...
| Keywords: | (±)17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 128914-47-6 |
| MW: | 320.5 D |
From 196.00€
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17(R)-HETE
Item number: Cay10010637-25
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific...
| Keywords: | 17R-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 183509-24-2 |
| MW: | 320.5 D |
From 196.00€
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CAY10535
Item number: Cay10010396-25
TPalpha and TPbeta are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPbeta is believed to be responsible for vascular endothelial growth factor-induced...
| Keywords: | N-(tert-butylcarbamoyl)-2-(3-methoxyphenoxy)-5-nitrobenzenesulfonamide |
| Application: | TP receptor antagonist |
| CAS | 945716-28-9 |
| MW: | 423.4 D |
From 48.00€
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