- Search results for Cay10010549
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18 products were found matching "Cay10010549"!
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Item number: Cay10010249-5
The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-8, an isoquinolinesulfonamide protein kinase (PK) inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for...
Keywords: | Protein Kinase Inhibitor H-8, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide, dihydrochloride |
Application: | PKA inhibitor, PKG inhibitor |
CAS | 113276-94-1 |
MW: | 338.3 D |
From 50.00€
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Item number: Cay10010749-5
PIK-90 is a potent and cell permeable phosphoinositide 3-kinase (PI3K) inhibitor (IC50 = 11, 350, 18, and 58 nM for p110 subunit isoforms alpha, beta, gamma, and delta, respectively). Through this action, PIK-90 reduces chemotaxis and induces apoptosis in chronic lymphocytic leukemia B cells. It also blocks...
Keywords: | PIK-85, N-(2,3-dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide |
Application: | PI3K inhibitor |
CAS | 677338-12-4 |
MW: | 351.4 D |
From 26.00€
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Item number: Cay10010495-10
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2alpha in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with...
Keywords: | (+)-16-m-Chlorophenoxy tetranor PGF2alpha methyl amide, D-Cloprostenol methyl amide,... |
Application: | FP receptor agonist, luteolytic agent |
MW: | 438 D |
From 97.00€
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Item number: Cay10010-5
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 14152-28-4 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10010854-96
Three known isoforms of SREBP (sterol regulatory element binding protein) transcription factors have been characterized: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1c acts primarily to activate genes required for fatty acid synthesis, such as acetyl-CoA carboxylase, fatty acid synthase, and long chain fatty acid...
Keywords: | Sterol Regulatory Element-Binding Protein-1 Assay Kit |
Application: | SREBP-1 DNA binding |
Species reactivity: | human, mouse, rat |
661.00€
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Item number: Cay10009549-100
Fatty acid binding protein 4 (FABP4) is a member of the intracellular lipid-binding protein (iLBP) family. It is composed of a beta-barrel, which forms the lipid-binding site, and two alpha-helices that form a lid on the beta-barrel. FABP4 is primarily expressed in adipocytes but has also been found in activated...
Keywords: | ALBP, ALBP, FABP4, AFABP, AFABP, A-FABP, A-FABP, Fatty acid-binding protein 4, Fatty acid-binding protein 4, Adipocyte... |
Application: | WB |
MW: | 18,8 kD |
472.00€
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Item number: Cay10010494-500
Tranylcypromine is an irreversible, mechanism-based inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 20.7 µM in a cell-free assay). It also irreversibly inhibits monoamine oxidase A (MAO-A) and MAO-B with IC50 values of 2.3 and 0.95 µM, respectively. Tranylcypromine inhibits nucleosomal demethylation of...
Keywords: | trans-2-Phenylcyclopropylamine, 2-PCPA, (1R,2S)-rel-2-phenyl-cyclopropanamine, monohydrochloride |
Application: | LSD1 inhibitor |
CAS | 1986-47-6 |
MW: | 169.7 D |
From 34.00€
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Item number: Cay10010499-500
Prostaglandin A2 (PGA2) blocks cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. It has antitumor effects, targeting scaffold/matrix attachment region-binding protein 1 (SMAR1) through an Hsp70-dependent mechanism. PGA2 also induces apoptosis in HL-60 cells. Prostaglandin A2-biotin (PGA2-biotin) is...
Keywords: | PGA2-biotin, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oyl-N'-biotinoyl-1,5-diaminopentane |
Application: | Bioactive lipid assays |
MW: | 644.9 D |
From 50.00€
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Item number: Cay10014-5
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1beta converting enzyme (ICE, Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia.Formal Name: N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxo-propyl]-L-alaninamide. CAS Number: 178603-78-6. Synonyms:...
Keywords: | N-Ac-Tyr-Val-Ala-Asp-CMK, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxo-propyl]-L-alaninamide |
Application: | Caspase-1 inhibitor |
CAS | 178603-78-6 |
MW: | 541 D |
From 52.00€
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Item number: Cay10049-100
6(S)-Lipoxin A4 (6(S)-LXA4) is an isomer of the trihydroxy fatty acid LXA4 (Cay-90410). It is formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) through double lipoxygenase-catalyzed reactions initiated by either 5-lipoxygenase (5-LO) followed by 12- or 15-LO, with a leukotriene A4 (LTA4)...
Keywords: | 5(S),6(S),15(S)-TriHETE, 5(S),6(S)-Lipoxin A4, 6(S)-LXA4, 6-epi-Lipoxin A4,... |
Application: | Bioactive lipid studies |
CAS | 94292-80-5 |
MW: | 352.5 D |
From 368.00€
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Item number: Cay10010547-50
2-Arachidonoyl glycerol (2-AG) is an endogenous ligand that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and is involved in the regulation of a broad range of neurotransmitter signalling functions with implications in neurodegenerative diseases, pain, cancer, and obesity. Levels...
Keywords: | 5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester |
Application: | Fatty acid amide hydrolase inhibitor |
CAS | 439146-24-4 |
MW: | 360.5 D |
From 110.00€
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Item number: Cay10010541-50
Sphingosines are long-chain base precursors of cellular sphingolipids and are used directly in the synthesis of ceramide. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally. L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed...
Keywords: | L-threo-Sphingosine C18, 2S-amino-4E-octadecene-1,3S-diol |
Application: | PKC inhibitor |
CAS | 25695-95-8 |
MW: | 299.5 D |
From 164.00€
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