- Search results for Cay10010548
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14 products were found matching "Cay10010548"!
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Item number: Cay10010248-5
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth...
Keywords: | GCP 5126, Malonoben, NSC 242557, RG-50872, SF 6847, Tyrphostin 9, Tyrphostin AG-17,... |
Application: | EGF receptor kinase inhibitor |
CAS | 10537-47-0 |
MW: | 282.4 D |
From 38.00€
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Item number: Cay10010948-5
Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator. DL-Propargyl glycine (PAG) is an irreversible inhibitor of the H2S synthesizing enzyme cystathionine-gamma-lyase (CSE). PAG blocks H2S synthesis activity in rat liver preparations with an IC50 value...
Keywords: | PAG, 2-amino-4-pentynoic acid, monohydrochloride |
Application: | CSE inhibitor |
CAS | 16900-57-5 |
MW: | 149.6 D |
From 23.00€
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Item number: Cay10010854-96
Three known isoforms of SREBP (sterol regulatory element binding protein) transcription factors have been characterized: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1c acts primarily to activate genes required for fatty acid synthesis, such as acetyl-CoA carboxylase, fatty acid synthase, and long chain fatty acid...
Keywords: | Sterol Regulatory Element-Binding Protein-1 Assay Kit |
Application: | SREBP-1 DNA binding |
Species reactivity: | human, mouse, rat |
661.00€
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Item number: Cay10010-5
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 14152-28-4 |
MW: | 336.5 D |
From 48.00€
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Item number: Cay10010486-500
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity. 14,15-EE-8(Z)-E is a structural analog of 14(15)-EET that demonstrates potent vasodilator...
Keywords: | 14,15-Epoxyeicosa-8(Z)-enoic Acid, 13[(2R,3S)-3-pentyloxiranyl]-8Z-tridecenoic acid |
Application: | Vasodilator agonist |
CAS | 519038-93-8 |
MW: | 324.5 D |
From 65.00€
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Item number: Cay10010484-500
5(Z),14(Z)-Eicosadienoic Acid is a novel omega-6 C20:2 fatty acid. The more common 11(Z),14(Z)-eicosadienoic acid competitively inhibits inosine 5'-monophosphate dehydrogenase (Ki = 3.1 µM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki = 3.0 µM). Also, serum levels of eicosadienoic acids...
Keywords: | 5Z,14Z-eicosadienoic acid |
Application: | LTB4 receptor antagonist |
CAS | 122055-58-7 |
MW: | 308.5 D |
From 114.00€
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Item number: Cay10009548-100
Fatty acid binding protein 2 (FABP2) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids. Members of this protein family exhibit high-affinity for small lipophilic ligands and were named according to the tissue from which they were initially isolated. Studies suggest...
Keywords: | Fatty Acid Binding Protein 2, I-FABP, Intestinal-FABP |
Application: | WB |
MW: | 19,3 kD |
465.00€
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Item number: Cay10014-5
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1beta converting enzyme (ICE, Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia.Formal Name: N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxo-propyl]-L-alaninamide. CAS Number: 178603-78-6. Synonyms:...
Keywords: | N-Ac-Tyr-Val-Ala-Asp-CMK, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxo-propyl]-L-alaninamide |
Application: | Caspase-1 inhibitor |
CAS | 178603-78-6 |
MW: | 541 D |
From 52.00€
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Item number: Cay10010547-50
2-Arachidonoyl glycerol (2-AG) is an endogenous ligand that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors and is involved in the regulation of a broad range of neurotransmitter signalling functions with implications in neurodegenerative diseases, pain, cancer, and obesity. Levels...
Keywords: | 5Z,8Z,11Z,14Z-eicosatetraenoic acid, oxiranylmethyl ester |
Application: | Fatty acid amide hydrolase inhibitor |
CAS | 439146-24-4 |
MW: | 360.5 D |
From 110.00€
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Item number: Cay10010541-50
Sphingosines are long-chain base precursors of cellular sphingolipids and are used directly in the synthesis of ceramide. Sphingosine can exist in four stereoisomers, however only D-erythro-sphingosine occurs naturally. L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed...
Keywords: | L-threo-Sphingosine C18, 2S-amino-4E-octadecene-1,3S-diol |
Application: | PKC inhibitor |
CAS | 25695-95-8 |
MW: | 299.5 D |
From 164.00€
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Item number: Cay10010540-50
1,2,3-Triheneicosanoyl glycerol is a triacylglycerol containing heneicosanoic acid (Cay-22593) groups at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in human breast milk samples and triacylglycerols in rat heart.Formal Name: heneicosanoic acid,...
Keywords: | Glycerol Triheneicosanoate, TG(21:0/21:0/21:0), Triheneicosanoin, heneicosanoic acid, 1,2,3-propanetriyl ester |
Application: | Fatty acid quantification internal standard |
CAS | 26536-14-1 |
MW: | 1017.7 D |
From 50.00€
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Item number: Cay10010518-5
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
Keywords: | NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole |
Application: | 15-LO inhibitor |
CAS | 4079-26-9 |
MW: | 237.3 D |
From 65.00€
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