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PD 146176
PD 146176

Item number: Cay10010518-25

PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
Keywords: NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole
Application: 15-LO inhibitor
CAS 4079-26-9
MW: 237.3 D
From 65.00€ *
Review
Acenocoumarol
Acenocoumarol

Item number: Cay10010569-25

Acenocoumarol is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase (VKOR) (IC50 = 1.5 and 5.8 nM for VKORC1 and VKORC1L1, respectively). Acenocoumarol also inhibits a variety of VKOR mutants in cell-based reporter assays (IC50s =...
Keywords: Acenocoumarin, G-23350, Nicoumalone, Sinthrome(R), Sintrom(R),...
Application: Anticoagulant, vitamin K antagonist
CAS 152-72-7
MW: 353.3 D
From 77.00€ *
Review
Etheroleic Acid
Etheroleic Acid

Item number: Cay10005119-25

Etheroleic acid is a divinyl ether oxylipin. It is a metabolite of linolenic acid that is formed in plants via 13-lipoxygenase-mediated formation of 13(S)-HpODE (Cay-48610) or (±)13-HpODE (Cay-10704) followed by conversion to the divinyl ether by divinyl ether synthase. Etheroleic acid (30 µM) is fungicidal against...
Keywords: 12-[(1E)-1-hexenyloxy]-9Z,11E-dodecadienoic acid
Application: Divinyl ether oxylipin
CAS 169217-38-3
MW: 294.4 D
From 220.00€ *
Review