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PD 146176
PD 146176

Item number: Cay10010518-25

PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
Keywords: NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole
Application: 15-LO inhibitor
CAS 4079-26-9
MW: 237.3 D
From 65.00€ *
Review
CAY10564
CAY10564

Item number: Cay10010527-25

S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low molecular weight species such as S-nitrosoglutathione (GSNO) and S-nitrosocysteine (CysNO)....
Keywords: 4-(p-chlorophenyl)-1,3,2-Oxathiazolylium-5-olate, 4-chloro-4-phenyl-1,3,2-oxathiazolidine-5-one
Application: NO donor
MW: 215.7 D
From 43.00€ *
Review
AS-604850
AS-604850

Item number: Cay10010175-25

Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of PI at the three position of the inositol ring to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kgamma is a class 1B PI3K that is composed of a p110 catalytic subunit and a p101 or p84 regulatory subunit, whereas...
Keywords: 5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylene]-2,4-thiazolidinedione
Application: PI3Kgamma inhibitor
CAS 648449-76-7
MW: 285.2 D
From 35.00€ *
Review