3 products were found matching "Cay10010498-%25"!
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CB-13
Item number: Cay10010398-25
CB-13 is a dual agonist of the CB1 (IC50 = 15 nM) and CB2 (IC50 = 98 nM) receptors. In rats, oral CB-13 (3 mg/kg) potently blocks CB1-dependent neuropathic mechanical hyperalgesia, shows limited brain penetration, and exhibits good oral bioavailability. CB-13 does not possess genotoxic potential, as indicated by...
| Keywords: | CRA-13, 1-naphthalenyl[4-(pentylox)-1-naphthalenyl]-methanone |
| Application: | Dual CB1 / CB2 receptor agonist |
| CAS | 432047-72-8 |
| MW: | 368.5 D |
From 74.00€
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HA-130
Item number: Cay10498-25
HA-130 is a reversible inhibitor of autotaxin, completely blocking the hydrolysis of the substrate bis-pNPP with an IC50 value of 28 nM. It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...
| Keywords: | B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid |
| Application: | Reversible autotaxin inhibitor |
| CAS | 1229652-21-4 |
| MW: | 463.3 D |
From 97.00€
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(S)-AM1241
Item number: Cay10490-25
(S)-AM1241 binds to cannabinoid (CB) receptors and is selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively, in a membrane assay using human receptors). (S)-1241 acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 (EC50 = 131 nM) than at rat...
| Keywords: | (-)-AM1241, (2-iodo-5-nitrophenyl)[1-[[(2S)-1-methyl-2-piperidinyl]methyl]-1H-indol-3-yl]-methanone |
| Application: | Cannabinoid receptor agonist |
| CAS | 444912-53-2 |
| MW: | 503.3 D |
From 85.00€
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