3 products were found matching "Cay10010497-%25"!

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Lubiprostone
Lubiprostone

Item number: Cay10010487-25

Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
Keywords: RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid
Application: ClC-2 activator
CAS 136790-76-6
MW: 390.5 D
From 84.00€ *
Review
N,N'-Dicyclohexylurea
N,N'-Dicyclohexylurea

Item number: Cay10004971-25

Epoxyeicosatrienoic acids (EETs), lipid mediators synthesized from arachidonic acid by cytochrome P-450 epoxygenases, are converted by soluble epoxide hydrolase (sEH) to the corresponding dihydroxyeicosatrienoic acids (DHETs). N,N' Dicyclohexylurea (DCU) is a selective sEH inhibitor with IC50 values of 160 and 90 nM...
Keywords: DCU, NSC 17013, N,N'-dicyclohexyl-urea
Application: sEH inhibitor
CAS 2387-23-7
MW: 224.3 D
From 27.00€ *
Review
Ionomycin
Ionomycin

Item number: Cay10004974-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 60.00€ *
Review